background: oral contraceptive pills are among the most popular contraceptive methods, but the fear of cancer and cardiovascular disease overshadows its continuous use among women. this study aimed to define the association between consumption patterns of combined oral contraceptives among women with breast cancer. materials and methods: this is an analytical case–control study conducted on 175...

background and aim: oropharyngeal cancer is a significant cause of death and disability worldwide. in iran it is the 13th and 17th most common cancer found in men and women, respectively. the aim of this study was to investigate etiological factors and clinical features of lesions related to oropharyngeal cancers over a 5-year period in tehran. materials and methods: in this retrospective cross...

background: the mapping of the malignization mechanism is still incomplete, but oxidative stress is strongly correlated to carcinogenesis. in our research, using fuzzy logic, we aimed to estimate the oxidative stress related-cancerization risk of the oral potentially malignant disorders. methods: serum from 16 patients diagnosed (clinical and histopathological) with oral potentially malignant d...

it has been argued that oral lichen planus (olp) may increase the risk of oral cancer. patients with olp may be at an increased risk for developing of oscc (oral squamous cell carcinoma). here, the author reports a case of olp initially presenting with a clearly benign olp lesion that transformed into oscc over a course of 18 months. this report may provide a clear evidence for olp lesion as a ...

conclusions we conclude that oral cancer is etiologically related to the interaction between smoking and drinking. results the smoking as well as alcohol drinking rates in the subjects of the case group were significantly higher than the controls. of smoking types, bidi (a hand rolled cigarette) (or = 4.1, 95% ci = 2.4-6.9), and among alcohol types, hard liquor (or = 2.6, 95% ci = 1. 4-6.4), cou...

there is a continuing need to identify new agents that are active in ovarian cancer. etoposide is a derivative of the plant alkaloid epipodophyllotoxin. the availability of etoposide in oral preparation allows prolonged administration by the oral route. in this study, activity and toxicity of etoposide in women with recurrent ovarian cancer are described from a case series of women with recurre...

Many types of cancers develop in the oral and maxillofacial region. Squamous cell carcinoma is the most common cancer and constitutes over 90 percent of these tumors. Malignant transformation is a genetic process, which later makes a phenotyping change at the cellular level. Some cancers such as oral squamous cell carcinomas (OSCCs) develop from pre-malignant lesions and conditions. Despite adv...