There is limited experience in lung transplantation. The indications of lung transplantation in children are different compared with adults. There are some special problems in pediatric lung transplantation such as donor shortage, size discrepancy, growth potential of transplanted lung and hemodynamic problems. Although some of these problems have been solved, only 2% of lung and hearth-lung tr...

Brain-dead donor organ transplantation has been available to children in Japan since the 2010 revision of the Organ Transplant Law. Of the 50-60 brain-dead donor organ transplants performed annually in Japan, however, very few (0-4 per year) are performed in children. Again, while those receiving liver, heart, and kidney transplants are reported to fare better than their counterparts in the res...

Background: Organ transplantation is the most successful therapy for end-stage organ disease since it increases quality of life and expectancy. For these reasons, over 107,000 patients were on waitlist in United States a transplant 2022. Unfortunately, only 42,887 transplants performed, annually, 7000 kidney list die or are too sick to transplant. To solve this severe shortage, use deceased rec...

More than 100,000 individuals are on the waiting list to receive a lifesaving transplant, but many of them will not receive the organ they need. Legislation has been passed to support organ donation--the current organ procurement system in the United States is governed by the Uniform Anatomical Gift Act of 1968 and the National Organ Transplant Act of 1984--but a shortage of donated organs rema...

Reducing the shortage of organ donations to meet demands patients on waiting list has being a major challenge in transplantation. Because shortage, matching decision is most critical assign limited viable organs “suitable” patients. Currently, decisions are only made by scores calculated via scoring models, which built first principles. However, these models may disagree with actual post-transp...

The grave inadequacy of current international attempts to curtail organ trafficking signals the need for a new approach in the form of a fundamental paradigm shift. Instead of continuing to focus efforts solely on criminalization, countries must devise a broad scheme aimed at decreasing organ shortages. These shortages fuel the illegal organ market, as people desperate for life-saving transplan...

The main, universal problem for transplantation is organ scarcity. The gap between offer and demand grows wider every year and causes many patients in waiting list to die. In Spain, 90% of transplants are done with organs taken from patients deceased in brain death but this has a limited potential. In order to diminish organ shortage, alternative strategies such as donations from living donors,...

OBJECTIVES Organ transplantation is one of the most remarkable therapeutic advances in modern medicine; it started as an experiment and has become a life-saving practice. We briefly describe the major milestones of this multidisciplinary clinical science, the challenges that it still faces, and we consider the crucial contribution that its example could set for other medical fields. MATERIALS...