Scans of the Drosophila melanogaster genome have identified organophosphate resistance loci among those with the most pronounced signature of positive selection. In this study, the molecular basis of resistance to the organophosphate insecticide azinphos-methyl was investigated using the Drosophila Genetic Reference Panel, and genome-wide association. Recently released full transcriptome data w...

Copyright: © 2012 ElZalabany LM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract The present case reports the first ever case of homicidal poisoning due to injection of an organophosphate insec...

Organophosphate (OP) and organophosphate ester (OPE) adducts of albumin are valuable biomarkers for retrospective verification of exposure. In the present study, our goal was to determine whether OPE flame retardants (OPE FRs) and OPE plasticizers can covalently bind to human serum albumin (HSA), which would allow the resulting adducts to be used to evaluate exposure. Eleven OPE FRs and plastic...

Cytochrome P450 monooxygenases are involved in insecticide resistance in insects. We previously observed an increase in CYP6P7 and CYP6AA3 mRNA expression in Anopheles minimus mosquitoes during the selection for deltamethrin resistance in the laboratory. CYP6AA3 has been shown to metabolize deltamethrin, while no information is known for CYP6P7. In this study, CYP6P7 was heterologously expresse...

18 Netting window screens and eave baffles (WSEBs), allowing mosquitoes to enter but not exit 19 from houses, were assessed as an alternative to indoor residual spraying (IRS) for malaria vector 20 control. WSEBs treated with water, the pyrethroid lambda-cyhalothrin (LC), or the 21 organophosphate pirimiphos-methyl (PM), with and without a binding agent (BA) for increasing 22 insecticide persis...

Background Most national dengue control programmes rely extensively on insecticides to control the mosquito vectors of this disease. Objectives The objective of this review is to describe current knowledge of the extent of insecticide resistance in dengue vectors and the potential impact of this resistance on control activities. Methods We searched Web of Science and PubMed for studies that inc...

INTRODUCTION Acetamiprid is a potent and a relatively new neonicotinoid insecticide. Animal studies have indicated that it has a low toxicity to mammals. Despite wide usage, human exposure resulting in toxicity is quite limited, and this is the first report in the English literature about acute acetamiprid poisoning in humans. CASE DETAILS We herein describe two cases of acute poisoning with ...

The negative effects of a commonly applied systemic insecticide, neonicotinoid, on the honey bee Apis mellifera L. are of great concern worldwide, as the use of the chemical is expanding. Recently, special attention has been paid to the sublethal effects of insecticides. An increasing number of studies has identified sublethal effects on the honey bee in the laboratory or in experimental cages,...