nosed malignancy, and second leading cause of cancer related deaths in the United States. Among them, approximately half of the patients develop incurable condition with no effective treatment. Current therapy for advanced prostate cancer is largely based on androgen deprivation. However, as with androgen ablation therapy, the responses are generally of short duration and resistant to therapy e...

RATIONALE The reactions of NO(+) with volatile organic compounds (VOCs) in Selective Reagent Ionization Time-of-Flight Mass Spectrometry (SRI-TOF-MS) reactors are relatively poorly known, inhibiting their use for trace gas analysis. The rationale for this product ion distribution study was to identify the major product ions of the reactions of NO(+) ions with 13 organosulfur compounds and 2 org...

The non-methane organic compounds (NMOCs) released from municipal solid waste (MSW) landfills impose significant impact on the environment and human health. It is necessary to investigate the fugitive emission of NMOCs from MSW landfills for helping control NMOC emissions and reduce the environmental impacts. This study was focused on the concentration distribution of NMOCs on the operating and...

Twenty-seven selenium compounds and sixteen structurally related organosulfur compounds were tested for quinone reductase (QR) and glutathione-S-transferase (GST) inducing activity in murine hepatoma (Hepa 1c1c7) cells. Sixteen selenium compounds were able to double QR activity, and seven of them also doubled GST activity. The nine most potent compounds, dimethyl diselenide, 2,5-diphenyl- selen...

Organosulfur compounds are the biologically active components of allium vegetables. Many health benefits have been ascribed to them, including inhibition of carcinogenesis. Inasmuch as several of these thioallyl compounds are quite unstable and others are rapidly inactivated in the body, we have investigated one of the stable components present in aged garlic extract, S-allylmercaptocysteine (S...

The Allium genus includes approximately 500 species. Commonly used allium vegetables include garlic, onion, leeks, chives, scallions which are used all over the world in different delicacies. Some allium vegetables have been employed for millenia in the traditional medical practice to treat cardiovascular diseases. They have been shown to have applications as antimicrobial, antithrombotic, anti...