Contamination by hazardous substances is one of the main environmental problems in eastern Gulf Finland, Baltic Sea. A trilateral effort to sample and analyse heavy metals (HMs), polycyclic aromatic hydrocarbons (PAHs), organotins from bottom sediments 2019–2020 were conducted along with harvesting historical data Russian, Estonian Finnish waters. We suggest that input still occurs ship traffic...

In the analysis of organotin compounds, derivatization is required in order to achieve more volatile compounds prior to the use of techniques based on GC separation. Derivatization can be considered as one of the main critical steps in organotin analysis, since low yields of derivatization and losses of analytes can easily occur at this stage, and lead to an underestimation of their content in ...

Polymethylhydrosiloxane (PMHS) made hypercoordinate by KF(aq) allows Me(3)SnH to be recycled during a Pd(0)-catalyzed hydrostannation/Stille cascade. Starting with a variety of alkynes, in situ vinyltin formation is followed by Stille reaction with aryl, styryl, benzyl, or vinyl electrophiles present in the reaction mixture. Both inter- and intramolecular versions of the process are possible wi...

The third countrywide survey on imposex and organotin contamination in the rock shell was conducted in 93 locations along the Japan coast between September 1996 and January 1999. The percentage occurrence of imposex was still high in 86 locations whereas no or rare instances of imposex were found in the remaining seven locations. Severe imposex symptoms were observed in the rock shell populatio...

Surface sediment samples were analyzed for organotins namely tributyltin (TBT), dibutyltin and monobutyltin from six areas located in the Gulf of Ca ́diz (14 stations), Spain. The total butyltin ranged between undetected and 1,580 ng Sn g. TBT generally prevailed in most of the samples, suggesting fresh inputs of butyltin compounds and/or less degradation of TBT. The observed levels of butyltins...

Azocyclotin and cyhexatin are pesticides commonly used in mite control. However, these organotin compounds (OTC) highly harmful to the aquatic ecosystem supposedly mobile soil. In addition not existing defined rules of use, few studies have been carried out on organotins’ behavior environmental Liquid chromatography has pointed for OTC quantitation because gas chromatography’s thermal stability...

Stannin (Snn) is a highly conserved, 88-amino acid protein that may mediate the selective toxicity of organotins. Snn is localized in tissues with known sensitivity to trimethyltin (TMT), including the central nervous system, immune system, spleen, kidney and lung. Cells in culture that do not express Snn show considerable resistance to TMT toxicity. In vitro, Snn peptide can bind TMT in a 1:1 ...

Organotins are among the most common marine pollutants in the world, as they are widely used as antifouling paint on ships and fishing nets. It has been reported that organotin preferentially accumulates in the central nervous system, especially in the retinal neurons of marine organisms including fish. In this study, we investigated the effects of waterborne tributyltin (TBT) on early-stage de...

Organotin compounds such as triphenyltin (TPT) and tributyltin (TBT) act as endocrine disruptors through the peroxisome proliferator-activated receptor γ (PPARγ) signaling pathway. We recently found that TPT is a particularly strong agonist of PPARγ. To elucidate the mechanism underlying organotin-dependent PPARγ activation, we here analyzed the interactions of PPARγ ligand-binding domain (LBD)...