Eighty patients were treated with either amikacin or netilmicin in a prospective randomized study of serious gram-negative bacillary infections, including 11 due to gentamicin-resistant pathogens. Thirty-six treated with netilmicin and 35 treated with amikacin were evaluable for efficacy or toxicity, or both. The overall groups differed significantly only in age. There were no significant diffe...

These days cochlear implantation is the accepted modality to rehabilitate deafened people. Meningitis is still a life threatening disease which may lead to deafness due to sole disease or secondary to ototoxic drugs used to stop the disaster [1]. Sepsis and/or meningitis may harm neonates whom are taking care in nurseries. TEOAE neonatal hearing screening programs are unable to find all of thes...

regardless of severity, earlier intervention to correct hearing loss in children improves speech development and conversational abilities. a cross-sectional study was performed on 230 neonates who were at risk of hearing loss in tehran university of medical sciences hospitals between september 2000 and february 2002. hearing was examined before the 3rd month by auditory brainstem responses (abr...

Results: 132 (16%) newborn had some risk indicators for hearing loss. NICU stay, low Apgar score, mechanical ventilation, lower birth weight less than 1500g and use of ototoxic drugs were the most frequenty risk indicators. A total of 51 (6%) newborns refer in the TEOAE test in at least one ear, and among them, 16 (31%) had a risk indicator for hearing loss. There was a statistically significan...

Address correspondence to: Medical University of South Carolina, Judy R. Dubno, Department of Otolaryngology-Head and Neck Surgery, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425-5500 US, Phone: (843) 792-7978, Fax: (843) 792-7736, [email protected]. In addition to its high prevalence, age-related hearing loss was considered a significant area of scientific focus because of its complex etiol...

BACKGROUND A significant number of medications that are prescribed by doctors to treat cancers, tuberculosis and infections are ototoxic. Disclosure of ototoxic risks is ethical practice as patients have the right to be properly informed about and involved in decisions about their health care. Often, doctors fail to disclose such information. AIM This research investigated whether a group of ...

Hair cells (HCs) are the sensory preceptor cells in the inner ear, which play an important role in hearing and balance. The HCs of organ of Corti are susceptible to noise, ototoxic drugs, and infections, thus resulting in permanent hearing loss. Recent approaches of HCs regeneration provide new directions for finding the treatment of sensor neural deafness. To have normal hearing function, the ...

The growing increase in age-related hearing loss (ARHL), with its dramatic reduction in quality of life and significant increase in health care costs, is a catalyst to develop new therapeutic strategies to prevent or reduce this aging-associated condition. In this regard, there is extensive evidence that excessive free radical formation along with diminished cochlear blood flow are essential fa...

<p class="abstract">With the advent of COVID-19 pandemic, there has been a myriad long-term complications in post-COVID patients. In these patients, one rare but dreaded symptoms reported is sudden onset sensorineural hearing loss (SNHL) that mostly during active infection. We followed up with patients our outpatient department and came across patient SNHL. conducted literature search Pub...

A method for the continuous perfusion of the perilymphatic space of the inner ear in the guinea pig is described. Artificial perilymph is supplied to the cochlea and drained away through a tubing system while flow rates from 10 microliters/min to 0.3 ml/min are established by gravity syphon pressure. Techniques are also presented which allow control over the temperature of the perfusate and ov...