Premature Ovarian Failure (POF) defined as functional stop of ovaries before the age of 40. It is a common cause of infertility in women that characterized by primary or secondary amenorrhea, high gonadotropin levels and estrogen level declining in patients. Factors that reduce follicle or defect in the follicle growth stimulating mechanism defined as numerous complication factors that they can...

Background Ovarian tissue cryopreservation is an option for patients who require immediate gonagonadotoxic treatment of cancers. when there is insufficient time to conduct ovulation induction This procedure can be used in patients with genetic mutations with a high risk for premature ovarian failure.This strategy is the only option for fertility preservation in prepubertal girls or in women who...

Introduction: Premature Ovarian Failure (POF) is cessation of ovarian functions before the age of 40 years old with consequent cessation of menstruation. Objective of study: The aim of this study was to evaluate the association between Premature Ovarian Failure and sexual dysfunctions and outcome of management with tibolone. Patients and Methods: Thirty-one women with Premature Ovarian Failure ...

objective: to determine the efficacy of ovarian drilling in pco patients who failed to achieve pregnancy with medical treatment. methods and main results: 75 patients with a diagnosis of pco of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. the other methods like bromocriptin, gonadotropins, gnrh -a and metformin had been given to these patie...

Ovarian cancer has the poorest prognosis among all gynecological cancers. 1,2 Besides the concealed onset of ovarian cancer and the high tendency to abdominal dissemination and metastasis, frequent recurrence and resistance to chemotherapy are also the main reasons for treatment failure of ovarian cancer. A large number of clinical trials proved that platinum­based chemotherapy plus paclitaxel ...

OBJECTIVE To investigate the incidence of ovarian failure after pulse cyclophosphamide treatment in systemic lupus erythematosus (SLE) and to compare this with two control groups: SLE patients treated with azathioprine, and a healthy age matched population. METHODS All women patients with SLE treated with pulse cyclophosphamide in our department were identified and questioned concerning menst...

OBJECTIVE To examine the effect of longstanding juvenile idiopathic arthritis (JIA) on menstrual irregularity and the incidence of premature ovarian failure in women. METHODS Women with longstanding JIA who had abnormal or absent menstrual cycles had their circulating levels of gonadotrophins measured to check for the presence of ovarian failure. Disease demographics and subsets, function, ag...