Blood-gas (Pao2) and hemodynamic responses to the inhalation of oxygen were studied in 60 patients with acute myocardial infarction. Patients who were not in heart failure on admission and did not develop signs of heart failure with n the next 5 days achieved the same Pa02 level while breathing 100% oxygen as did patients without acute myocardial infarction. Patients with pulmonary edema or car...

Malignant tumours often display hypoxic tissue areas where the oxygen tension is < 7 mm Hg. Studies in this field have proved that the hypoxic state boosts tumour progression and aggressive behaviour. In tissue culture experiments "in vitro" oxygenation was found to inhibit in itself the proliferation of cells of healthy tissues as well as benign and malignant tumours. It is a very important ob...

Blood-gas (Pao2) and hemodynamic responses to the inhalation of oxygen were studied in 60 patients with acute myocardial infarction. Patients who were not in heart failure on admission and did not develop signs of heart failure with n the next 5 days achieved the same Pa02 level while breathing 100% oxygen as did patients without acute myocardial infarction. Patients with pulmonary edema or car...

Lung injury resulting from inhalation of smoke or chemical products of combustion continues to be associated with significant morbidity and mortality. Combined with cutaneous burns, inhalation injury increases fluid resuscitation requirements, incidence of pulmonary complications and overall mortality of thermal injury. While many products and techniques have been developed to manage cutaneous ...

BACKGROUND The continuous infusion of prostacyclin has been shown to improve exercise capacity and survival in patients with primary pulmonary hypertension (PPH). Inhalation of iloprost, a stable analog of prostacyclin, might be an alternative therapy for PPH, selectively acting on the pulmonary vascular bed through ventilation-matched alveolar deposition of the drug. We investigated the short-...

Background Adherence to inhalation therapy is a critical determinant of the success of asthma management. However, in practice, no adherence to inhalation therapy is very common in asthmatics. The effects of adherence to inhalation therapy in asthma is less known about the relationship between medication adherence and quality of life in these patients. The aim of this study is to assess the fac...

We have studied the effects of inhalation of 95 to 100% oxygen on the surface morphology of the bronchi and bronchioles of adult mice, using scanning electron microscopy. Denudation of cilia and truncation of the remaining cilia were commonly observed during high oxygen exposure. Bleb formation, a "moth-eaten" appearance of the non-ciliated cell surface and desquamation of unidentified cells we...

Developing highly efficient catalysts for the oxygen reduction reaction (ORR) is key to the fabrication of commercially viable fuel cell devices and metal-air batteries for future energy applications. Herein, we review the most recent advances in the development of Pt-based and Pt-free materials in the field of fuel cell ORR catalysis. This review covers catalyst material selection, design, syn...