Benzoic acid and some related compounds are able to increase the metabolism of mycobacteria (Bernheim, 1941). The oxygen uptake and carbon dioxide production of the pathogenic strains H-37 and B, are greatly accelerated when small amounts of benzoic or salicylic (o-hydroxybenzoic) acid are added to the bacterial suspensions. Other hydroxybenzoic acids as well as aminobenzoic acids are without e...

incorporation of this acid in vitamin K 2 23 and vitamin K t 4 in bacteria and higher plants. Degradation of labeled vitamin K 2 after feeding shikimic acid (-U-1 4C) has shown that the intact ring of this acid is incorporated into the benzenoid moiety of this naphthoquinone 2 ' 3 . fn contrast, the degradation studies on lawsone 1 indicated that the ring atoms of shikimic acid (-U-1 4C) are tr...

Five phenolic compounds, 4-hydroxybenzoic acid methyl ester (1), vanillic acid methyl ester (2), 4-hydroxy benzaldehyde (3), 4-hydroxybenzoic acid (4) and ferulic acid (5), and four flavonoids, 5,5'-dihydroxy-4',6,7-trimethoxyflavanone (6), luteolin (7), vitexicarpin (8) and artemetin (9), were isolated from fruits and leaves of Vitex rotundifolia L. The biological activities of these nine comp...

Abstract: Coenzyme Q (Q), an essential component of eukaryotic cells, is synthesized by several enzymes from the precursor 4-hydroxybenzoic acid. Mutations in six of the Q biosynthesis genes cause diseases that can sometimes be ameliorated by oral Q supplementation. We establish here that Coq6, a predicted flavin-dependent monooxygenase, is involved exclusively in the C5-hydroxylation reaction....

Strains of Pseudomonas stutzeri (CINNS) and Pseudomonas putida (CINNP and CINNW) isolated from soil with cinnamic acid as the sole carbon source were found to be simultaneously adapted to grow on phenylpropionic and p-hydroxybenzoic acids. In cinnamic acid-grown cultures, phenylpropionic acid was isolated. A catabolic plasmid of approximately equal to 75 kilobase pairs encoding the metabolism o...