hand eczema is a common distressing skin problem. it is an immune reaction to haptens. thus, substances that inhibit immune system can be effective in the treatment of hand eczema. in this study, topical fumaric acid 5% cream is compared with topical steroid in the treatment of hand eczema. patients with hand eczema were randomly divided into two groups. one group received fumaric acid 5% in a ...

OBJECTIVE To examine the reasons for resistance to treatment in cases of palmoplantar psoriasis, and also to compare the frequency of delayed-type hypersensitivity to common sensitizers with those cases of psoriasis without palmoplantar involvement. SUBJECTS AND METHODS One hundred and three patients with resistant palmoplantar psoriasis were examined for a possible drug reaction, fungal infe...

The inheritance of Olmsted syndrome that is a very rare congenital with transgredient palmoplantar keratoderma is distinguished by the presence of massive hyperkeratosis with fissured skin and periorificial chaps. It usually appears during the early life and mostly in male pateints. Herein we report a case of Olmsted syndrome which is associated with ichthyosis and somatic type of delusion duri...

background: allergic diseases including asthma, allergic rhinitis (ar) and eczema are common chronic diseases in children. the purpose of this study was to determine the prevalence of asthma, ar and eczema in sari, iran. methods: this study was carried out on all elementary schools selected as a cluster from february 2010 to july 2010 in sari, north of iran. a questionnaire was provided accordi...

Although only a small area of the body is affected in palmoplantar psoriasis or psoriasis of the palms and soles, this condition causes considerable functional impairment due to hyperkeratosis, fissures, and erythema, and occasionally inflammation and pustules. These symptoms may seriously interfere with the patient’s quality of life and may be disabling. Moreover, the lack of a standard treatm...

Palmoplantar psoriasis is a chronic disease, which is very resistant to treatment and often leads to severe disabilities. Photochemotherapy employing psoralens combined with UVA irradiation (PUVA) is a well-accepted therapy for palmoplantar psoriasis. Its topical application (bath PUVA; cream PUVA) avoids the typical side effects of orally applied psoralens. We compared the efficacy of cream PU...

BACKGROUND Palmoplantar pustular psoriasis is often recalcitrant to therapy. Here we evaluated the therapeutic effect of alitretinoin in patients with recalcitrant palmoplantar pustular psoriasis and investigated subsequent immunopathological alterations. METHODS Seven patients with palmoplantar pustular psoriasis were treated with oral alitretinoin 30 mg once daily for 12 weeks. Efficacy was...

BACKGROUND Foot eczema often occurs in combination with hand eczema. However, in contrast to the situation with hand eczema, knowledge about foot eczema is scarce, especially in occupational settings. OBJECTIVE To evaluate the prevalence of foot eczema and associated factors in patients with hand eczema taking part in a tertiary individual prevention programme for occupational skin diseases. ...