In the daily drudgery of clinical practice, every now and then we come across a patient who is sure that a particular drug is affecting his or her skin in a peculiar way. However, to our brains, trained to recognize common drug eruptions, it seems fantastic that any drug could cause side effects such as digitate dermatosis, [1] mycosis fungoides, [2] leukemoid reaction, [3] leg ulcer [4] or eve...

Mycosis fungoides is the most common form of primary cutaneous lymphoma, with three phases: erythematous, infiltrative and tumour phase. In contrast with Sézary syndrome, the course is often slow and skin lesions may not be distinctive for a longer period of time and may resemble lesions occurring in the course of other dermatoses, such as eczema, large plaque parapsoriasis, atopic dermatitis o...

Clinical, immunohistological, and molecular biological data suggest the chronic dermatosis small plaque parapsoriasis (SPP) to be a precursor of mycosis fungoides (MF). However, most data are contradictory and confusing due to inexact definition of SPP. Recently, clonal T cells were detected in skin and blood samples of early MF. Because demonstration of identical T-cell clones in skin and bloo...

Background: Diagnosis of the early phase of mycosis fungoides (MF) is sometimes difficult. Loss of CD7 expression is considered a distinguishing characteristic of MF. The aim of this study was to determine the range of CD7 expression in MF and compare the results with benign inflammatory dermatosis and equivocal cases of possible MF. Methods: During a period of 30 months, we examined 15 patient...