carvacrol is one of the main components of the eo of some labiatae (laminaceae) members like oregano, thyme and savory. carvacrol has a lot of health benefits for example, antibacterial, and antioxidant activity.we synthesized some silicon derivatives of carvacrol, and characterized them by standard methods. then the monomer of dimethylvinylsilyl carvacrol was synthesized. copolymer of this mon...

patient noncompliance to current tuberculosis (tb) therapy owing to multidrug administration daily leads to treatment failure and emergence of multidrug resistant and extensively drug resistant tb. to avoid the daily dosing, application of nanotechnology is the only viable solution by virtue of sustained release of drugs. other potential advantages of the system include the possibility of selec...

recent advances in nanotechnology have rapidly developed new therapeutic and diagnostic concepts in all aspects of medicine. magnetic nanoparticles (mnps) can be simultaneously functionalized and guided by a magnetic field, thus providing promising tools for several biomedical applications. mnps contrast agents at low concentrations offer the potential to significantly improve existing methods o...

Biodegradable and biocompatible polymers are widely used for the encapsulation of drug molecules. Various particulate carriers with different sizes and characteristics have been prepared by miscellaneous techniques. In this review, we reported the commonly used preformed polymer based techniques for the preparation of micro and nano-structured materials intended for drug encapsulation. A descri...

Present review on the topic explores the different techniques of spherical agglomeration employed in pharmaceutical sciences and their potential applications in developing new particulate systems of drug. Spherical agglomeration is a particle engineering technique which transforms the fine crystals into spherical particles in a single step. These techniques applied in development of new systems...

Objective(s): Multifunctional nanomedicine is the new generation of medicine, which is remarkably promising and associated with the minimum toxicity of targeted therapy. Distribution and transport of nanoparticles (NPs) in the blood flow are essential to the evaluation of delivery efficacy. Materials and Methods: In the present study, we initially designed a phantom based on Murray’s mini...

conventional transdermal drug delivery systems (tdds) have been designed for drug delivery through the skin. these systems use the permeability property of stratum corneum, the outermost surface layer of the skin. applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

chitosan with excellent biodegradable and biocompatible characteristics has received attention as an oral drug delivery vehicle for controlled-release formulations. in this study an enteric-coated capsule containing theophylline-chitosan beads based on 23 factorial designs was prepared as a colon drug delivery system. the theophylline-chitosan gel beads were formulated by adding the drug-contai...

niosomes, non-ionic surfactant vesicles (nsvs), are the hydrated lipids composed mainly of different classes of non-ionic surfactants, introduced in the seventies as a cosmetic vehicle. nowadays, niosomes are used as important new drug delivery systems by many research groups and also they are effective immunoadjuvants which some commercial forms are available in the market. these vesicles rece...

carbon nanotubes (cnts) are high aspect ratio allotropes of carbon. because of their unique physical and chemical characteristics, they are nominated for a vast variety of applications in the biomedical field. their very low solubility is the only problem of them which is solved by different methods of functionalization. after discoveries in the last few years of the capacity of cnts to penetra...