نتایج جستجو برای: passive immunotherapy

تعداد نتایج: 102860  

2011
Donna M Wilcock Qun Zhao Dave Morgan Marcia N Gordon Angela Everhart Joan G Wilson Jennifer E Lee Carol A Colton

While the presence of an inflammatory response in AD (Alzheimer’s disease) is well known, the data on inflammation are conflicting, suggesting that inflammation either attenuates pathology, exacerbates it or has no effect. Our goal was to more fully characterize the inflammatory response in APP (amyloid precursor protein) transgenic mice with and without disease progression. In addition, we hav...

Journal: :Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 2005

2015
Teruyo Arato Takashi Daimon Yuji Heike Ken Ishii Kyogo Itho Shinichi Kageyama Yutaka Kawakami Eiichi Nakayama Keiya Ozawa Noriyuki Sato Hiroshi Shiku Masahiro Takeuchi Kenzaburo Tani Koji Tamada Ryuzo Ueda Yoshiyuki Yamaguchi Takeharu Yamanaka Hiroki Yamaue Masaki Yasukawa Toyotaka Iguchi Shigehisa Kitano Yoshihiro Miyahara Yasuhiro Nagata Masanori Noguchi Takeshi Terashima Takeo Asano Motohiro Asonuma Hiroaki Ikeda Kazuhiro Kakimi Kazutoh Takesako Masanori Tanaka Kohei Amakasu Akira Yamada Naozumi Harada Taiki Aoshi Etsushi Kuroda Kouji Kobiyama Daisuke Muraoka Naoya Yamazaki Aya Kuchiba Shiro Tanaka Hirofumi Michimae Tomomi Yamada Kenichi Hanada Hideho Okada Naoko Takebe Naoto Hirano Satoshi Okumura Daisaku Sato Masayoshi Shibatsuji Teruhide Yamaguchi

The development of cancer immunotherapies is progressing rapidly with a variety of technological approaches. They consist of "cancer vaccines", which are based on the idea of vaccination, "effector cell therapy", classified as passive immunotherapy, and "inhibition of immunosuppression", which intends to break immunological tolerance to autoantigens or immunosuppressive environments characteriz...

Journal: :Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2017
Farhad Heshmati

The first session of the congress was entitled “in the memory of ean Jacque Lefrère”, eminent professor of Hematology and Virology nd researcher. He was professor of Hematology at the Paris Descartes Univerity, director of the National Institute of Blood Transfusion, national xpert in transfusion and transfusion security, prions, viruses and lood related transmissible agents. He published more ...

Journal: :Cancer research 2012
Takuro Noguchi Takuma Kato Linan Wang Yuka Maeda Hiroaki Ikeda Eiichi Sato Alexander Knuth Sacha Gnjatic Gerd Ritter Shimon Sakaguchi Lloyd J Old Hiroshi Shiku Hiroyoshi Nishikawa

Monoclonal antibody (mAb) therapy against tumor antigens expressed on the tumor surface is associated with clinical benefit. However, many tumor antigens are intracellular molecules that generally would not be considered suitable targets for mAb therapy. In this study, we provide evidence challenging this view through an investigation of the efficacy of mAb directed against NY-ESO-1, a widely e...

Journal: :Anales del sistema sanitario de Navarra 2004
S Inogés M Rodríguez Calvillo A López Díaz de Cerio N Zabalegui I Melero A Sánchez Ibarrola E Rocha M Bendandi

The continuous search for therapeutic approaches that improve the conventional treatments of neoplasms, together with an improved understanding of the immune system, has led in recent years to the development of Immunotherapy. Basically, a distinction can be made between two forms of immunotherapy: passive immunotherapy, which consists in the transfer of antibodies or cells previously generated...

Journal: :Critical care medicine 2010
Thomas C Luke Arturo Casadevall Stanley J Watowich Stephen L Hoffman John H Beigel Timothy H Burgess

The world is experiencing a pandemic of swine-origin influenza virus H1N1. A vaccine to prevent disease is now available, and millions have or will become ill before they can be vaccinated. The ability to use swine-origin influenza virus vaccines as a public health tool has been described as a "race against time." Oseltamivir and related drugs are being used in an effort to reduce morbidity and...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Anna S Gardberg Lezlee T Dice Susan Ou Rebecca L Rich Elizabeth Helmbrecht Jan Ko Ronald Wetzel David G Myszka Paul H Patterson Chris Dealwis

Amyloid aggregates of the amyloid-beta (Abeta) peptide are implicated in the pathology of Alzheimer's disease. Anti-Abeta monoclonal antibodies (mAbs) have been shown to reduce amyloid plaques in vitro and in animal studies. Consequently, passive immunization is being considered for treating Alzheimer's, and anti-Abeta mAbs are now in phase II trials. We report the isolation of two mAbs (PFA1 a...

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