OBJECTIVE To assess vitreous and plasma changes of vascular endothelial growth factor A (VEGF-A), adrenomedullin (ADM) and endothelin-1 (ET-1) in proliferative diabetic retinopathy (PDR). PATIENTS AND METHODS 9 patients with PDR in type 2 diabetes (T2DM) and 11 age-matched non-diabetic patients were enrolled. The levels of VEGF-A, ADM and ET-1 were measured using an enzyme (ELISA) and a radio...

Abstract We present LT-PDR , a lattice-theoretic generalization of Bradley’s property directed reachability analysis (PDR) algorithm. identifies the essence PDR to be an ingenious combination verification and refutation attempts based on Knaster–Tarski Kleene theorems. introduce four concrete instances LT-PDR, derive their implementation from generic Haskell experimentally evaluate them. also c...

conclusions this study represented an increasing rate of mdr p. aeruginosa in burn and wound samples. efflux mexab genes were detected in all mdr and pdr strains. the p. aeruginosa strain isolated from burn cases showed higher drug resistance and pdr resistance was only noted in a burn sample. materials and methods one-hundred and fifty p. aeruginosa were isolated from burn and wound infections...

BACKGROUND Epigenetic variation has been linked to several human diseases. Proliferative diabetic retinopathy (PDR) is a major cause of vision loss in subjects with diabetes. However, studies examining the association between PDR and the genome-wide DNA methylation pattern are lacking. Our aim was to identify epigenetic modifications that associate with and predict PDR in subjects with type 1 d...

PURPOSE Recent studies revealed that immunological mechanisms play a prominent role in the pathogenesis of proliferative diabetic retinopathy (PDR). Given the importance of the immune response in PDR and the significance of the programmed death 1 (PD-1) pathway as an immune regulatory pathway, the aim of this study is to determine the expression and functional characteristics of the PD-1 pathwa...

First, we briefly introduce the technologies of PDR (Pedestrian Dead Reckoning) that can be used to track the location and orientation of a pedestrian. Secondly, we show some enhancement of the PDR to improve its performance on accuracy. Finally, we describe the applications of the PDR.

PURPOSE To assess the relationship between intraocular soluble heparan sulfate (HS) concentration and age in subjects with and without diabetic retinopathy. METHODS Vitreous from subjects with idiopathic maculopathies (n=17), i.e., macula hole or epiretinal membrane, or nonproliferative diabetic retinopathy (non-PDR; n=5) and aqueous humor from subjects with PDR (n=16), non-PDR (n=7), or cata...

INTRODUCTION During cardiac surgery with cardiopulmonary bypass (CPB) haemodilution occurs. Hepatic dysfunction after CPB is a rare, but serious, complication. Clinical data have validated the plasma-disappearance rate of indocyanine green (PDR ICG) as a marker of hepatic function and perfusion. Primary objective of this analysis was to investigate the impact of haemodilutional anaemia on hepat...

BACKGROUND Pigment epithelium-derived factor (PEDF), a glycoprotein with potent neuronal differentiating activity, was recently found to inhibit advanced glycation end product (AGE)-induced retinal hyperpermeability and angiogenesis through its antioxidative properties, suggesting that it may exert beneficial effects on diabetic retinopathy by acting as an endogenous antioxidant. However, the i...

Université de la Méditerranée, URMITE UMR 6236, CNRS-IRD, Faculté de Médecine et de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille cedex 05, France, NAFRI, Ministry of Agriculture and Forestry, Government of Lao PDR, Vientiane, Lao PDR, CSIRO Sustainable Ecosystems, Canberra, Australia, Wellcome Trust-Mahosot Hospital-Oxford Tropical Medicine Research Collaboration, Microbiology Laboratory, Maho...