OBJECTIVE To determine whether repetitive and cumulative exposure to low-frequency pulsed electromagnetic fields (PEMF) targeting painful feet can reduce neuropathic pain (NP), influence sleep in symptomatic diabetic peripheral neuropathy (DPN), and influence nerve regeneration. DESIGN Randomized, double-blind, placebo-controlled parallel study. SETTING Sixteen academic and clinical sites i...

Pulsed electromagnetic fields (PEMFs) have been used clinically to slow down osteoporosis and accelerate the healing of bone fractures for many years. The aim of this study is to investigate the effect of PEMFs on the proliferation and differentiation potential of human bone marrow mesenchymal stem cells (BMMSC). PEMF stimulus was administered to BMMSCs for 8 h per day during culture period. Th...

Inflammatory cytokines play a dominant role in the pathogenesis of disc degeneration. Pulsed electromagnetic fields (PEMF) are noninvasive biophysical stimulus that has been used extensively in the orthopaedic field for many years. However, the specific cellular responses and mechanisms involved are still unclear. The objective of this study was to assess the time-dependent PEMF effects on pro-...

Background: Low-intensity pulsed electromagnetic fields (PEMF) have been shown to improve gait parameters in frail older adults. 1 Furthermore, the continuous exposure PEMF (up year) demonstrated produce progressive improvements self-selected speed adults at risk of falling. 2 Objectives: To investigate effects two different treatment regimens on physical performances presenting with rheumatoid...

The objective of this study was to determine whether short exposure to pulsed electromagnetic fields (PEMF) accelerates bone repair and peri-implant bone formation in a rat tibial model at different times. Sixty Wistar rats were employed. Sterile custom fabricated commercially pure cylinder threaded titanium implants were placed in the right tibial crest, and an osteotomy was performed in the l...

Application of pulsed electromagnetic fields (PEMF) has been used in growth and repair of non-union bone fractures. The similarities between the fibrocartilage callus in non-union bone fractures and the secondary cartilage in the mandibular condyle, both histologically and functionally, lead naturally to study the effects of PEMFs on growth in the condyle. The purposes of this study were: (1) t...

Arthritis refers to more than 100 disorders of the musculoskeletal system. The existing pharmacological interventions for arthritis offer only symptomatic relief and they are not definitive and curative. Magnetic healing has been known from antiquity and it is evolved to the present times with the advent of electromagnetism. The original basis for the trial of this form of therapy is the intera...

Background: This study investigated the effects of extremely low frequency (ELF) pulsed electromagnetic field (PEMF) radiation on the growth of bacterium Staphylococcus aureus (ATCC 25923) that plays a versatile role in infecting wounded tissues. The viability of these bacteria (number of live cells as colony-forming units (CFUs)) was measured before and after the ELF PEMF exposures to quantify...

UNLABELLED The 'complex neural pulse'(TM) (CNP) is a neuromodulation protocol employing weak pulsed electromagnetic fields (PEMF). A pioneering paper reported an analgesic effect in healthy humans after 30 minutes of CNP-stimulation using three nested whole head coils. We aimed to devise and validate a stimulator with a novel design entailing a multitude of small coils at known anatomical posit...

Electromagnetic fields are considered to potentially affect embryonic development, but the mechanism is still unknown. In this study, human embryonic stem cell (hESC) line HUES-17 was applied to explore the mechanism of exposure on embryonic development to pulsed electromagnetic field (PEMF) for 400 pulses at different electric field intensities and the differentiation of HUES-17 cells was obse...