STUDY OBJECTIVE To analyse simultaneously the effect of several risk factors for peptic ulcer. DESIGN Cohort study where all patients with new or incident peptic ulcers in a well defined population were registered for a seven year period. The follow up started with a comprehensive health survey including a questionnaire on diet, lifestyle, psychological and social conditions, and health. Rela...

The goal of research. To analyze some features peptic ulcer the stomach and duodenum in children, depending on type constitution. Material methods We examined 58 children aged 12-18 years with a diagnosis and/or duodenum, who underwent endoscopic examination, Hp was detected biopsy aero test. Results. Peptic disease more often asthenic (67.2%), less hypersthenic (17.3%) normosthenics (15.5%). V...

Blood group A was found to be associated with gastric cancer in the 1950s. Strikingly, for peptic ulcers an increased risk has been shown for blood group O. However, previous investigations have generally been poorly conducted and have failed to take a unifying approach to these observations. Using the Scandinavian Donations and Transfusions (referred to as "SCANDAT") database, the authors esta...

Peptic ulcers are a broad term that includes ulcers of gastrointestinal tract. The formation of peptic ulcers is due to the presence of acid, peptic activity in gastric juice and a breakdown in mucosal defenses. There are two main factors that can disrupt the mucosal resistance to injuryare, nonsteroidal anti-inflammatory drugs and H. pylori infection. A number of anti-ulcer drugs such as proto...

OBJECTIVES To review some aspects of the etiopathogenesis of peptic ulcerous disease especially on the basis of studies on its correlation with Helicobacter pylori (H. pylori). METHODS A search was made in the data bases MEDLINE, LILACS and PubMed, and in Brazilian and foreign books, referring to the incidence and prevalence of infection by H. pylori and of peptic ulcerous disease in various ...

Imbalance between exogenous damaging agents and protective factors in the gastro-duodenum tract can lead to peptic ulcer disease. Herbal medicines could be an effective treatment human gastric ulcers. This study aimed investigate effect of AGAR-HP hard capsules on cysteamine-induced gastric-duodenal ulcers experimental rats. The animals were divided into five groups: Group 1 (control) group 2 (...

Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are curative techniques for gastric neoplasm; ESD has advantages over EMR regarding en bloc resection of large-sized lesions and submucosal fibrosis. Although ESD is widely considered a safe technique, complications including bleeding and perforation remain major concerns. While coagulation therapy after ESD and the u...

BACKGROUND The benefits of the Helicobacter pylori test-and-treat strategy are attributable largely to the cure of peptic ulcer disease while limiting the use of endoscopy. AIM To reappraise the test-and-treat strategy and empirical proton pump inhibitor therapy for the management of uninvestigated dyspepsia in the light of the decreasing prevalence of H. pylori infection, peptic ulcer diseas...

Peptic ulcer predicts gastric cancer. It is controversial if peptic ulcers predict other gastrointestinal cancers, potentially related to Helicobacter pylori or shared lifestyle factors. We hypothesized that gastric and duodenal ulcers may have different impact on the risk of gastrointestinal cancers. In a nationwide cohort study using Danish medical databases 1994-2013, we quantified the risk ...