BACKGROUND An imbalance in circulating angiogenic factors plays a central role in the pathogenesis of preeclampsia. METHODS AND RESULTS We prospectively studied 616 women who were evaluated for suspected preeclampsia. We measured plasma levels of antiangiogenic soluble fms-like tyrosine kinase 1 (sFlt1) and proangiogenic placental growth factor (PlGF) at presentation and examined for an assoc...

background: the children’s body composition status is an important indicator of health condition evaluated through their body mass index (bmi). we aimed to provide standardized percentile curves of bmi in a population of iranian children and adolescents. we assessed the nationally representative of sample populations from tehran. materials and methods: a total sample of 14,865 children aged 7-1...

We first show that any 1−α bootstrap percentile confidence interval for a proportion based on a binomial random variable has an infimum coverage probability zero for any sample size. This result is then extended to intervals for the difference, the relative risk and the odds ratio of two proportions as well as other types of bootstrap intervals. © 2013 Elsevier B.V. All rights reserved.

OBJECTIVE Emergency department overcrowding sometimes results in diversion of ambulances to other locations. We sought to determine the resulting prehospital delays for cardiac patients. METHODS Data on consecutive patients with chest pain who were transported to Toronto hospitals by ambulance were obtained for a 4-month period in 1997 and a 4-month period in 1999, which represented periods o...

BACKGROUND The safety of 2-h preoperative clear liquid fasts has not been established for overweight/obese pediatric day surgical patients. Healthy children and obese adults who fasted 2 h have small residual gastric fluid volumes (GFVs), which are thought to reflect low pulmonary aspiration risk. We sought to measure the prevalence of overweight/obesity in our day surgery population. We hypoth...

Abstract Background Beta-thalassemia is a common hereditary hemoglobinopathy, which is a reason of microcytic hypochromic anemia. Patients with major thalassemia require multiple blood transfusions. This study evaluated growth in thalassemic patient and relationship with ferritin level. Materials and Methods This is a cross sectional study on seventy patients (36 boys, 34girls) with transfu...

OBJECTIVES To estimate the association between isolated second-trimester short femur length and fetal growth restriction as well as other adverse perinatal outcomes. METHODS We conducted a retrospective cohort study of patients with singleton gestations presenting for sonography between 16 and 24 weeks' gestation from 1990 to 2009. Cases of aneuploidy, skeletal dysplasia, and major anomalies ...

The aim of this paper is to project extreme precipitation events in an arid and a semiarid station. In order to project climate change based on general circulation models (GCMs), we have applied LARS-WG[1] downscaling tool. This stochastic weather generator down-scaled the climate of two synoptic stations using HADCM3 model and A2 emission scenario for 2040. We extracted extreme precipitation e...