INTRODUCTION Studies have shown the regulatory role of Leptin in bone formation, its expression in adipose tissue as well as increased levels in circulation following the adminstration of inflammatory stimuli such as lipopolysaccharides (LPS). However, there is little data evaluating the role of Leptin in inflammatory periapical lesions. The aim of this study was to evaluate the presence and co...

PURPOSE The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). MATERIALS AND METHODS 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility stu...

The aim of this study was the radiographic evaluation of the apical and periapical region of dog teeth submitted to intracanal bacterial endotoxin (lipopolysaccharide, LPS), associated or not with calcium hydroxide. After removal of the pulp, 60 premolars were divided into four groups and were filled with bacterial endotoxin (group 1), bacterial endotoxin plus calcium hydroxide (group 2), salin...

Periapical lesions are among the most frequent periodontal pathologies in human teeth, generally called apical periodontitis. Apical periodontitis is a continuation of the endodontic space infection and it is manifested as a response of the host defense against the microbial action. It may determine local inflammation, hard tissue resorption, destruction of other periapical tissues. The prelimi...

persistent microorganisms in the root canal are known to cause endodontic treatments failure. overextended gutta-percha can also act as a periradicular tissue irritant, leading to large periapical lesions. retrieval of overextended gutta-percha with a nonsurgical approach can prove to be a challenge. this case describes the nonsurgical management of a large periapical lesion associated with ove...

OBJECTIVES The aim of the present study was to compare the accuracy of intraoral digital periapical radiography and cone beam computed tomography in the detection of periapical radiolucencies in endodontically treated teeth. MATERIAL AND METHODS Radiographic images (cone beam computed tomography [CBCT] scans and digital periapical radiography [PR] images) from 60 patients, achieved from Septe...

In the oral cavity, extranodal non-Hodgkin's lymphoma can occur in the periapical region either in the maxilla or mandible. Also, it can mimic inflammatory lesions that arise around the teeth apices such as periapical granuloma, radicular cyst and osteomyelitis. Misdiagnosis of lymphomas in the jaws may reduce the chance of successful treatment and worsen the prognosis. Therefore, any growth of...

A total of 149 periapical lesions were classified histologically into cysts, granulomas and other lesions. It was found that 53% were cysts, 39% were granulomas and 8% were other lesions. Of the 149 periapical lesions classified, 69 selected cases of cysts and granulomas were obtained and radiographic measurements of area (mm2), largest diameter (mm) and largest root-to-border distance (mm) wer...

AIM To determine the presence of various periapical pathologies and their association with the presence and extent of internal apical inflammatory root resorption in human teeth. METHODOLOGY A total of 75 root apices from extracted teeth with periapical lesions were examined. Semi-serial sections of soft tissue lesions were stained with HE. The lesions were classified as non-cystic or cystic,...