Retinoblastoma remains the most common pediatric intraocular tumor. While current therapies have significantly limited patient mortality, the focus has recently shifted towards eye-preserving treatments. These new eye-preserving therapies are particularly relevant to 40% of the RB cases that are bilateral. Periocular chemotherapy, selective ophthalmic artery infusion chemotherapy (SOAIC), and i...

Basal cell carcinoma (BCC) is the most common periocular skin cancer and can lead to significant morbidity. We assess the effectiveness of vismodegib, a first-in-class Hedgehog signaling pathway inhibitor, in the management of periocular and orbital BCCs based on clinical response, tolerability, and orbital content preservation. All patients with periocular or orbital BCCs who met criteria for ...

Periocular recognition has gained attention recently due to demands of increased robustness of face or iris in less controlled scenarios. We present a new system for eye detection based on complex symmetry filters, which has the advantage of not needing training. Also, separability of the filters allows faster detection via one-dimensional convolutions. This system is used as input to a periocu...

Merkel cell carcinoma (MCC) in the eyelid and periocular region can be treated surgically, in most cases, with preservation of the eye and reasonable visual function. Adjuvant radiation therapy, sentinel lymph node biopsy, and chemotherapy should be considered for MCC of the eyelid and periocular region, especially for larger tumors that are T2b or more advanced and lesions that present with re...

skin disorders comprise more than 35% of all occupationally related diseases. 90-95% of work-related dermatoses are contact dermatitis. effects of occupational dermatitis in the lives of workers are substantial. to plan any preventive program we need basic statistics of the problem, that we had no reliable one which includes a lot of industries in iran. therefore we decided to determine occupat...

A 5-month-old infant with bilateral advanced retinoblastoma underwent six cycles of systemic chemotherapy. In an attempt to salvage the second eye, three serial injections of periocular carboplatin were given for persistent vitreous seeding. Following the third injection, the patient developed periocular ecchymosis and magnetic resonance imaging demonstrated abnormal signal characteristics at t...