Introduction: India leads the world with largest number of diabetic subjects earning the dubious distinction of being termed the ‘diabetes capital of the world’. Oral manifestations of diabetes mellitus are devastating, these include gingival and periodontal diseases, bone loss, dental caries, alterations in salivary flow and others. Materials and methods: In our study, sample consists of 50 pa...

Periodontitis is defined as a chronic infectious disease caused by periodontal bacteria. Chronic periodontal inflammation results in alveolar bone loss and periodontal supportive tissue, eventually leading to tooth loss. Type 2 diabetes mellitus is mainly characterized by hyperglycemia because of impaired action of insulin. Though the etiology of the two diseases is different, number of reports...

Periodontitis and osteoporosis are two diseases found in both male and female population worldwide. The main characteristic of the two diseases is their increased intensity with age. Periodontitis is associated with resorption of the alveolar bone. Osteoporosis, as the highest degree of osteopenia, is characterized by bone loss leading to structural bone transformation. The association between ...

Porphyromonas gingivalis, a pathogen associated with periodontitis, bound to fibrinogen, fibronectin, hemoglobin, and collagen type V with a similar profile to that of its major virulence factor, the cell surface RgpA-Kgp proteinase-adhesin complex. Using peptide-specific, purified Abs in competitive inhibition ELISAs and epitope mapping assays, we have identified potential adhesin binding moti...

background and aims. periodontal disease is an inflammatory response in periodontal tissues, which results in tissue destruction, bone loss and eventually tooth loss. periodontal disease has the potential to affect pregnancy outcomes such as premature birth, low birth weight and preeclampsia. the aim of this study was to assess periodontal health knowledge, attitude, and practice of pregnant wo...

PURPOSE This study was performed to assess the correlation of calcified carotid atheromatous plaque (CCAP), the mandibular cortical index, and periodontal bone loss in panoramic radiographs. MATERIALS AND METHODS One hundred eighty-five panoramic radiographs with CCAP and 234 without this finding were evaluated by 3 observers for the presence of osseous changes related to osteoporosis and per...

BACKGROUND Recent studies suggest a possible association between periodontal disease and hypertension; however, prospective evidence is limited. METHODS The study population consisted of 31,543 participants of the Health Professionals' Follow-Up Study (HPFS) prospective cohort who were 40-75 years old at baseline, had no prior hypertension history and had complete baseline information on oral...

introduction radiographs provide unique information about the status of periodontium and permanent records of condition of bone throughout the course of the disease. interproximal images record the distance between the cementoenamel junction and the crest of the interradicular alveolar bone, more accurately. the aim of this study was to investigate the effect of different vertical angles of x-r...

A major virulence factor of Porphyromonas gingivalis is the extracellular noncovalently associated complexes of Arg-X- and Lys-X-specific cysteine proteinases and adhesins designated the RgpA-Kgp complexes. In this study we investigated the ability of RgpA-Kgp as an immunogen to protect against P. gingivalis-induced periodontal bone loss in the rat. Specific-pathogen-free Sprague-Dawley rats we...

Periodontal disease is one of the most prevalent chronic disorders worldwide. It is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss. Here, we focused on the role of adipokines, which are locally expressed by periodontal tissues, in the regulation of catabolic gene expression leading to periodontal inflammation. The expression of t...