L. Razenberg1, Y. van Gestel1, V. Lemmens1, J. De Wilt2, G. Creemers3, I.H.J. T. De Hingh4 Research & Epidemiology, Comprehensive Cancer Centre the Netherlands, Eindhoven, NETHERLANDS Department of Surgery, Radboud University Medical Centre, Nijmegen, NETHERLANDS Department of Internal Medicine, Catharina Hospital Eindhoven, Eindhoven, NETHERLANDS Department of Surgery, Catharina Hospital Eindh...

BACKGROUND Peritoneal carcinomatosis is a poor prognostic factor for patients with gastrointestinal, gynecologic, and pancreatic cancer. Cisplatin (CDDP) is among the most effective anti-cancer agents, although its adverse effects remain unresolved. For the treatment of peritoneal carcinomatosis with high-dose CDDP, it is necessary to design a new delivery system of CDDP that can decrease syste...

Patients with advanced gastric carcinoma, especially peritoneal dissemination, have a poor prognosis. Various treatments have been used for peritoneal dissemination of gastric cancer, but there is no effective therapy for this condition. At present, similar proprieties of chemokines between trafficking of leukocytes during immune and inflammatory reactions and organ selective migration of cance...

Calcified peritoneal implants have been attributed to various malignant and benign causes. We present an interesting case of a 32-year-old woman who presented with abdominal pain, distension and vaginal bleeding. Contrast-enhanced computed tomography revealed calcified peritoneal implants with a malignant ovarian mass. Histopathology showed an endodermal sinus tumor, a rare cause of calcified p...

We describe the case of a man who presented with back pain and acute kidney injury and was found to have bilateral ureteral obstruction, which initially corrected with ureteral stents. Imaging studies showed thickening of the bladder. Shortly thereafter, he developed obstructive jaundice, pancreatitis, recurrence of renal failure, and was diagnosed with advanced gastric cancer after a laparotom...

UNLABELLED PET is widely used at the clinical and preclinical levels for tumor assessment and evaluation of treatment efficacy. Here, we established and took advantage of a preclinical model of peritoneal carcinomatosis to evaluate the contribution of inflammatory infiltrating macrophages in tumor progression that was followed using (18)F-FDG PET. METHODS Groups of mice with peritoneal carcin...

AIMS AND BACKGROUND Pseudomyxoma peritonei is a rare disease characterized by a complete redistribution of mucin within the peritoneal cavity. It can be classified into three histologic groups: disseminated peritoneal adenomucinosis, peritoneal mucinous carcinomatosis, and an intermediate group. The aim of the present study was to evaluate the feasibility of cytoreductive surgery requiring peri...

Peritoneal carcinomatosis (PC) is a global challenge of modern oncology representing the most unfavourable scenario in diverse-locality tumourisation. Despite certain attention by oncological community, management PC patients currently palliative, which weakly promotes research into basic principles this morbidity. This literature review attempts to comprehensively cover problematic from perspe...

BACKGROUND Advanced head and neck squamous cell carcinomas frequently develop distant metastases to limited organs, including the lungs, bone, mediastinal lymph nodes, brain, and liver. Peritoneal carcinomatosis as an initial distant metastasis from hypopharyngeal squamous cell carcinoma is quite rare. CASE PRESENTATION A 75-year-old man diagnosed with hypopharyngeal squamous cell carcinoma a...

Peritoneal carcinomatosis is associated with poor prognosis in gastric cancer patients. Stage IV (GC) diagnosed 39.8 % of patients; local metastases without evidence distant occur only 18–20 stage The purpose the study was to estimate efficacy personalized chemotherapy combined modality treatment patients GC peritoneal carcinomatosis. Material and Methods. Cytoreductive surgery performed 70 dis...