Recent results of advanced experiments with sophisticated measurements of cosmic rays in the energy range of the so called knee at a few PeV indicate a distinct knee in the energy spectra of light primary cosmic rays and an increasing dominance of heavy ones towards higher energies. This leads to the expectation of knee-like features of the heavy primaries at around 100 PeV. To investigate in d...

La dinámica que subyace en los extremismos tiene como rasgo común la exclusión del otro a través discurso de odio. Una las claves para prevención extremismo violento (PEV) apunta trabajar desde políticas públicas prejuicios y estereotipos sustentan ideas conforman el discriminatorio. Este estudio expone un proyecto educativo marco estrategia PEV UNESCO literatura. propuesta se articula alrededo...

The IceCube experiment at South Pole consists of two detector components the IceTop air shower array on the surface and the neutrino telescope at depths from 1450 to 2450 meters below. Currently, 26 IceTop stations and 22 InIce strings are deployed. With the present size of the IceTop array, it is possible to measure cosmic rays with energies ranging from 0.5 PeV to 100 PeV. Coincident events b...

Genes normally resident in euchromatic domains are silenced when packaged into heterochromatin, as exemplified in Drosophila melanogaster by position effect variegation (PEV). Loss-of-function mutations resulting in suppression of PEV have identified critical components of heterochromatin, including proteins HP1, HP2, and histone H3 lysine 9 methyltransferase. Here, we demonstrate that this sil...

Although the Drosophila Y chromosome is degenerated, heterochromatic, and contains few genes, increasing evidence suggests that it plays an important role in regulating the expression of numerous autosomal and X-linked genes. Here we use 15 Y chromosomes originating from a single founder 550 generations ago to study the role of the Y chromosome in regulating rRNA gene transcription, position-ef...

Background: The pericardial effusion volume (PEV) does not possess a known regular shape. Therefore, the standard methods for volume estimation based on 2-D echooardiography can not be / / applied. This study was conducted to evaluate a new computer algorithm for acoustic quantification of PEV. Methods: Borders of the pericardial sac and the heart were identified either by hand tracing or with ...

A review of current status of theoretical paradigm and results of direct and indirect experiments to study cosmic rays through the knee region are presented and discussed. There is general agreement that the knee is around a PeV and that it reflects a rigidity cutoff. The composition of cosmic rays in the knee region is mixed and changing with energy. The two direct experiments, JACEE and RUNJO...

The effects of maternal deprivation on the somatotrophic axis and neuropeptide Y (NPY) neuronal system in the hypothalamus of female lambs were evaluated. Twelve-week-old lambs were divided into two groups: the control (lambs stayed with mothers) and maternally deprived (MD; lambs separated for 3 days from mothers). The expression of immunoreactive (ir) somatostatin in the neurons of the perive...

The vast majority of the >100 modifier genes of position-effect variegation (PEV) in Drosophila have been identified genetically as haplo-insufficient loci. Here, we describe pitkin(Dominant) (ptn(D)), a gain-of-function enhancer mutation of PEV. Its exceptionally strong enhancer effect is evident as elevated spreading of heterochromatin-induced gene silencing along euchromatic regions in varie...

The next ten years promise to be a particularly exciting decade for high energy neutrino astrophysics. The frontier of TeV and PeV energies is presently being tackled by large, expandable arrays constructed in open water or ice. Detectors tailored to record acoustic, radio, fluorescence or air shower signatures from neutrino interactions at PeV – EeV energy are being designed in parallel. Durin...