Two synthetic strategies for incorporating diiron analogues of [FeFe]-hydrogenases into short peptides via phosphine functional groups are described. First, utilizing the amine side chain of lysine as an anchor, phosphine carboxylic acids can be coupled via amide formation to resin-bound peptides. Second, artificial, phosphine-containing amino acids can be directly incorporated into peptides vi...

The effects of different types and concentrations of electron donors (glucose, starch, methanol and sodium acetate) on the formation of phosphine from anaerobic activated sludge that has been domesticated for a prolonged period were studied in small batch experiments. The results show that types and concentrations of electron donor have significant effects on the production of phosphine from an...

The objectives of this work were to assess phosphine resistance in insect populations (Tribolium castaneum, Rhyzopertha dominica, Sitophilus zeamais and Oryzaephilus surinamensis) from different regions of Brazil and to verify if the prevailing mechanism of phosphine resistance in these populations involves reduced respiration rates. Sixteen populations of T. castaneum, 15 of R. dominica, 27 of...

In their article McDaniel et al. (2005) presented three case studies, one involving an evaluation by Sciences International, Inc. (Pepelko et al. 2004), of which I am the president and CEO. This case study was related to the reregistration of phosphine by the U.S. Environmental Protection Agency (EPA). McDaniel et al. (2005) make two principal accusations: a) that I improperly used my status as...

The red flour beetle is a cosmopolitan pest of stored grain and stored grain products. The pest has developed resistance to phosphine, the primary chemical used for its control. The reproductive output of survivors from a phosphine treatment is an important element of resistance development but experimental data are lacking. We exposed mated resistant female beetles to 0.135 mg/L of phosphine f...

ingestion and inhalation of phosphine are 2 forms of toxicity and their clinical manifestation is extremely wide. a 22-year-old girl was admitted with complaints of nausea, vomiting and epigastric pain after eating lunch. she had a history of celiac disease. on arrival, she was alert and hemodynamically stable. there was not any abdominal tenderness or guarding. food poisoning treatment initiat...

In the title compound, [Cu(NCS)(C3H9PS)] n , the thio-cyanate ions bind the Cu(I) atoms covalently, forming infinite -Cu-SCN-Cu- chains parallel to the a axis. Each Cu(I) atom is also coordinated to a tri-methyl-phosphine sulfide group via a Cu-S bond. Two crystallographically independent chains propagate in opposite directions, and are held together in a ribbon arrangement by long bonds betwee...