The aim of this study is to examine the possibility to inactivate food pathogen Listeria monocytogenes by nonthermal antimicrobial treatment – photosensitization. L. monocytogenes was incubated with 5-aminolevulinic acid (ALA) (7.5 mM) for 0–2 h to produce endogenous photosensitizers and then illuminated with visible light. The LED-based light source used for the illumination of L. monocytogene...

21 Photodynamic inactivation (PDT) of Leishmania spp. requires cellular uptake of 22 photosensitizers, e. g. endocytosis of silicon (IV)-phthalocyanines (PC) axially substituted with 23 bulky ligands. We report here that, when substituted with amino-containing ligands, the PCs 24 (PC1 and PC2) were endocytosed and displayed improved potency against Leishmania tropica 25 promastigotes and axenic...

Photodynamic inactivation of microorganisms has emerged as a promising strategy to kill and eradicate pathogens. In this work, two polymers, TCP-P ZnTCP-P, were synthesized by oxidative polymerization 5,10,15,20-tetrakis [3-(N-ethylcarbazoyl)]porphyrin its complex with Zn(II). Solid polymers consist rods (diameter 100 nm, length ~100–500 nm) that form microporous structures on surface. UV-visib...

Bacteria are inactivated using a technique called photodynamic inactivation, which combines light with photosensitizer the right spectrum. The objective of this study is to ascertain e­ciency purple LEDs for photoinactivating Bacillus subtilis and Escherichia coli bacteria as well ideal LED exposure energy density. This involves exposing radiation. Two elements variation used during irradiation...

Novel multifunctional magnetic particles (MMPs) conjugated with photosensitizer and vancomycin were fabricated by surface modification of Fe(3)O(4) particles. The capacities to target, capture and inactivate pathogenic bacteria and good biocompatibility suggest that the MMPs have great potentials as photodynamic inactivation agents for serious bacterial contamination.