A novel scheme for fully scalable White Monte Carlo (WMC) has been developed and is used as a forward solver in the evaluation of experimental time-resolved spectroscopy. Previously reported scaling problems are avoided by storing detection events individually, turning spatial and temporal binning into post-simulation activities. The approach is suitable for modeling of both interstitial and no...

aKorea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.; bKorea Electrotechnology Research Institute (KERI), Ansan 15588, Korea ; cMedical Research Institute, Gangneung Asan Hospital, 38, Bangdong-gil, Sacheon-myeon, Gangneung, Korea; dAsan Biomedical Research Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; eDepartment of Radiolo...

Empirical data between 510 and 590 nm of diffuse reflected light from the pig heart in vivo have shown that myoglobin and cytochrome c absorption peaks with little apparent contribution of red blood cell (RBC) Hb. Monte Carlo simulations of photon migration in tissue were performed to compare the effects of myoglobin and cytochromes with those of blood Hb on photon pathlengths and diffuse refle...

We propose a comprehensive protocol for the performance assessment of photon migration instruments. The protocol has been developed within the European Thematic Network MEDPHOT (optical methods for medical diagnosis and monitoring of diseases) and is based on five criteria: accuracy, linearity, noise, stability, and reproducibility. This protocol was applied to a total of 8 instruments with a s...

We developed a novel method of measurement of the dynamic light scattering phase function of particles utilizing laser Doppler technique. We show the theoretical background, validation carried out on Monte Carlo data and proposition of measurement setup. OCIS codes: (290.5820) Scattering measurements; (170.3660) Light propagation in tissues, (170.5280) Photon migration, (170.3340) Laser Doppler...

Abstract Single-photon emitters are crucial building blocks for optical quantum technologies. Hexagonal boron nitride (hBN) is a promising two-dimensional material that hosts bright, room-temperature single-photon emitters. However, photo instability persistent challenge preventing practical applications of these properties. Here, we reveal the ubiquitous photobleaching hBN vacancy Independent ...

The vertical migration behaviour of diatom assemblages inhabiting Wadden Sea sediments near Dangast (Germany) was investigated using cryo-scanning electron microscopy. The diatom assemblages were dominated by small Navicula species. Intertidal sediments which were located at different distances from the high tide level or stayed submerged even throughout low tides were chosen. Samples were prep...

Naïve T cells continuously traffic to secondary lymphoid organs, including peripheral lymph nodes, to detect rare expressed antigens. The migration of T cells into lymph nodes is a complex process which involves both cellular and chemical factors including chemokines. Recently, the use of two-photon microscopy has permitted to track T cells in intact lymph nodes and to derive some quantitative ...

Two-photon microscopy is providing literal insight into the cellular dynamics of lymphoid organs and, guided by analysis of three-dimensional images, into mechanisms that underlie cell migration and antigen recognition in vivo. This review describes lymphocyte motility and antigen recognition in the native tissue environment and compares these results with a much more extensive literature on ly...