Background: Epstein-barr virus nuclear antigen 1 (EBNA1) plays a crucial role in Nasopharyngeal carcinoma (NPC), the most common cancer of head and neck cancer in Asian countries with high incidents. Sequence variations are of high frequency within the functionally important domains of EBNA-1, which have been classified into five subtypes: Phenotype (P)-ala, P-thr, V-val, V-leu and V-pro and ar...

BACKGROUND Although there is a sizeable body of evidence regarding the nature of hostile behaviours among clinicians in the nursing workplace, what is less clear is the nature of the relationship between these behaviours and patient care. To inform the development of appropriate intervention strategies we examine the level of evidence detailing the relationships between hostile clinician behavi...

Clinician-investigators, also called physician-scientists, offer critical knowledge and perspectives that benefit research on basic science mechanisms, improved diagnostic and therapeutic approaches, population and outcomes medicine, health policy, and health services, yet few clinically trained health professionals pursue a research career. Sustaining this workforce requires attention to the u...

Purpose: There are a few researches regarding the effects of Islamic fasting on visual system. The aim of this study was to investigate the effects of Ramadan fasting on the amplitude of accommodation (AA), near point of convergence (NPC), positive and negative fusional vergences (PFV and NFV, respectively) in visually healthy fasters. Methods: AA, NPC, PFV and NFV at far (6m) and near (40cm) w...

Patients suffering with various orofacial pain conditions are likely to seek advice and treatment from a family physician. Temporomandibular disorders (TMD) are common in the general population, and the clinician should be aware of the common associated signs and symptoms so that proper therapy can be provided. The family physician can often provide initial therapies that are effective in reduc...

The studies done on lung protective strategies in medical ventilators have shown that tidal volume of 6-ml/ kg predicted body weight protects the lungs a patient during invasive ventilation for acute respiratory distress syndrome (ARDS) patients intensive care unit. Corona virus disease 2019 has increased need mechanical ventilation, which are operated manually, changing settings ventilators. I...

conclusion this study has highlighted the anatomical variations of npc regarding its dimension, location and morphological appearance. cylindrical was the most common shape followed by funnel-shape, hourglass, and spindle, which were the other canal shapes with less frequency, respectively. the results suggest significant relationship between npc, and gender and dental status. the influence of ...

The mechanism of nasopharyngeal carcinoma (NPC) remains unclear. The present study investigated the abnormal expression of long non-coding (lnc)RNAs in NPC tissues and one NPC cell line to identify the involvement of lncRNAs in the tumorigenesis of NPC. Using a quantitative reverse transcription polymerase chain reaction (RT-qPCR), the expression of lncRNA C22orf32-1 in NPC tissues and an NPC c...