Following the characterization of hypoglycemic, gastric emptying inhibitory, and gastroprotective principles and the structure elucidation of calendasaponins A, B, C, and D, two new ionone glucosides (officinosides A and B), and two sesquiterpene oligoglycosides (officinosides C and D), were isolated from the flowers of Egyptian Calendula officinalis. The structures of the officinosides were el...

Interest in the chemical nature and mode of action of bacterial toxins has been renewed by the simultaneously announced crystallization of botulinal (1) and tetanal toxins (2) and the recent purification of several toxoids (3-5). Of these, crystalline Clostridium botulinurn type A toxin alone has been submitted to an apparently complete elementary and amino acid analysis (6), as well as to prel...