Results The most frequently found subtypes and recombinants were: B (40.4%), D (32.1%, presumably CRF19_cpx), C (9.5%) and CRF18_cpx (8.3%). The PI mutations, I54VML, M46IL and L90MVL were found in 61.7, 57.4 and 53.1% of cases, respectively. Whereas for RTI, primary mutations at positions M184V, T215Y, D67N, Y181C and K103N were present in 98.6, 67.1, 43.8, 47.5 and 40.9% of subjects, respecti...

The activation status of the guanosine triphosphate (GTP)-binding protein Ras is dictated by the relative intensities of two opposing reactions: the formation of active Ras-GTP complexes, promoted by guanine-nucleotide exchange factors (GEFs), and their conversion to inactive Ras-GDP as a result of the deactivating action of GTPase-activating proteins (GAPs). The relevance of phosphoinositide 3...

OBJECTIVES To examine the relationship between low maternal serum pregnancy-associated plasma protein-A (PAPP-A) and uterine artery pulsatility index (UtA-PI) at 11+0 to 13+6 weeks with subsequent development of pre-eclampsia (PE). METHODS UtA-PI and serum PAPP-A were measured in women attending for routine care at 11+0 to 13+6 weeks of gestation. In the population, 156 (1.9%) women developed...

OBJECTIVE To examine the distribution of uterine artery pulsatility index (UtA-PI) at 12, 22, 32 and 36 weeks' gestation in singleton pregnancies which develop pre-eclampsia (PE) and examine the performance of this biomarker in screening for PE. METHODS UtA-PI was measured in 92 712 singleton pregnancies at 11-13 weeks, in 67 605 cases at 19-24 weeks, in 31 741 at 30-34 weeks and in 5523 at 3...

chronic periodontitis (cp) and peri-implantitis (pi) are multifactorial diseases of tooth and implant supporting apparatus. bacterial invasion and consequent host immune response seem to play a role in relevant pathogenesis. the structural differences between tooth and implant pose preferential biofilm colonization. this study was aimed to compare the prevalence of bacteria in cp and pi. clinic...

for a ring endomorphism $alpha$ and an $alpha$-derivation $delta$, we introduce a concept, so called skew $pi$-armendariz ring, that is a generalization of both $pi$-armendariz rings, and $(alpha,delta)$-compatible skew armendariz rings. we first observe the basic properties of skew $pi$-armendariz rings, and extend the class of skew $pi$-armendariz rings through various ring extensions. we nex...

The Phosphate Transporter1 (PHT1) family of genes plays pivotal roles in the uptake of inorganic phosphate from soils. However, there is no comprehensive report on the PHT1 family in Zea mays based on the whole genome. In the present study, a total of 13 putative PHT1 genes (ZmPHT1;1 to 13) were identified in the inbred line B73 genome by bioinformatics methods. Then, their function was investi...

By S. MARCHI, D. GUIDOTTI, L. SEBASTIANI and R. TOGNETTI* BioLabs, Polo Sant’Anna Valdera, Scuola Superiore Sant’Anna, Viale Rinaldo Piaggio, I-56025 Pontedera (PI), Italy Aedit s.r.l., Viale Rinaldo Piaggio, I-56025 Pontedera (PI), Italy Dipartimento di Scienze e Tecnologie per l’Ambiente e il Territorio (STAT), Università degli Studi del Molise, Contrada Fonte Lappone, I-86090 Pesche (IS), It...