BACKGROUND Although European Society of Urogenital Radiology proposed the potential of multiparametric magnetic resonance imaging (MP-MRI) as a tool in the diagnostic pathway for prostate cancer (PCa) and published a unified scoring system named Prostate Imaging Reporting and Data System (PI-RADS version 1), these still need to be validated by real-life studies. OBJECTIVE To evaluate the role...

In this paper we prove that if two minimal Z actions of a Cantor set are related by a bounded orbit injection then the associated R suspension spaces are homeomorphic. We also prove a structural result about such suspension spaces. Namely, that they are a finite union of products of Cantor sets with polygons, Ci × Pi, after an identification on boundary, Ci × ∂Pi, with the action given by R on ...

In this study a novel structure for time-delay MIMO systems controller design is introduced. In this method decoupled Smith predictor (SP) controller is designed using Internal Model Control structure (IMC). In order to approximate decoupled system, step response model approximation is employed and simulated on MIMO multiple time-delay system. Moreover, to improve system performance from oversh...

BACKGROUND Progressive beta-cell dysfunction and beta-cell failure are fundamental pathogenic consequences of type 2 diabetes. Dipeptidyl peptidase-IV inhibitors may exhibit improvement on preclinical measures of both beta-cell function, homeostasis model assessment of beta-cell (HOMA-beta) index, and beta-cell dysfunction, proinsulin/insulin ratio (PI/IR), correlating to beta-cell survival. ...

OBJECTIVE The current study was designed to evaluate the sensitivity, feasibility, and effectiveness of the pallidal index (PI) serving as a biomarker of brain manganese (Mn) accumulation, which would be used as an early diagnosis criteria for Mn neurotoxicity. METHODS The weighted mean difference (WMD) of the PI between control and Mn-exposed groups was estimated by using a random-effects or...

We examine a new 2nd order integrator recently found by Omelyan et al. The integration error of the new integrator measured in the root mean square of the energy difference, 〈∆H2〉1/2, is about 10 times smaller than that of the standard 2nd order leapfrog (2LF) integrator. As a result, the step size of the new integrator can be made about three times larger. Taking into account a factor 2 increa...

Some analytical results concerning PI controller tuning based on integrator plus time delay models are worked out and presented. A method for obtaining PI controller parameters, Kp = α kτ , and, Ti = βτ , which ensures a given prescribed maximum time delay error, dτmax, to time delay, τ , ratio parameter δ = dτmax τ , is presented. The corner stone in this method, is a method product parameter,...