background and objective: clinical behavior of basal cell carcinoma (bcc) is known to be different according to histological growth pattern and basosquamous cell carcinomas (bsc) are known with their aggressive behavior and metastatic capacity. in this study, we evaluated bcl-2 and cyclin d1 expressions in bcc and bsc cases comparatively, to explore their predictive value on the aggressive beha...

BACKGROUND Basal cell carcinoma is the most frequent cancer in fair-skinned populations and dermoscopy is an important, non-invasive technique that aids in the diagnosis of Basal cell carcinoma. OBJECTIVES The aim of this study was to evaluate the relationship between histopathological subtypes and dermoscopic features of Basal cell carcinoma. METHODS This study included 98 patients with cl...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

Background: Skin cancer is the most common malignancy and makes upto about one third of all cancers diagnosed. The skin include nonmelanoma melanoma. majority head neck are cancers[1]. Out which BCC common. Basal cell carcinoma accounts for approximately 75% cases cancers. Older age male sex associated with higher risk developing basal carcinoma. occurs mostly on face , head, scalp, hands. Aims...

Basal cell carcinoma is the most common malignant neoplasm of skin in humans, originating from basal cells epidermis and its adnexa. It characterized histologically by uncontrolled proliferation that show similarity to normal cells. Chronic exposure ultraviolet (UV) radiation considered main risk factor development, sun-exposed skin, such as face upper extremities, location for appearance this ...