Lissoclimides are cytotoxic compounds produced by shell-less molluscs through chemical secretions to deter predators. Chlorinated lissoclimides were identified as the active component of a marine extract from Pleurobranchus forskalii found during a high-throughput screening campaign to characterize new protein synthesis inhibitors. It was demonstrated that these compounds inhibit protein synthe...

Arabinogalactan-proteins (AGPs) are complex glycoconjugates that are commonly found at the cell surface and in secretions of plants. Their location and diversity of structures have made them attractive targets as modulators of plant development but definitive proof of their direct role(s) in biological processes remains elusive. Here we overview the current state of knowledge on AGPs, identify ...

The use of a microorganism or its secretions to prevent plant disease offers an attractive alternative or supplement to synthetic fungicides for the management of plant disease. A strain BS062 was selected based on the inhibitory effect of mycelial growth of Botrytis cinerea, a major causal fungus of postharvest root rots in ginseng and gray mold disease in strawberry. The strain BS062 was clos...

BACKGROUND Clearing subglottic secretions has been proved to reduce ventilator-associated pneumonia. A manual method named the rapid flow expulsion maneuver was developed to clear subglottic secretions. This study evaluates its safety and effectiveness and analyzes the influential factors. METHODS This study was composed of 2 parts. In an in vitro study, secretions were instilled directly to ...

The amount of upper airway secretions removed by suction alone was compared to that removed after chest physiotherapy in six neonates with a clinically suspected problem of increased respiratory tract secretions. More secretions were removed after physiotherapy.

Experiments were done to investigate mechanisms of appearance of both 7 S and 11 S IgA in nasal secretions. Three IgA preparations, (a) 11 S IgA from nasal secretions, (b) 7 S IgA from homologous serum, and (c) 7 S IgA from autologous serum, were isolated, labeled, and injected intravenously into volunteers. The rate of disappearance from plasma and the extent and nature of their appearance in ...

BACKGROUND Biofilm accumulates within the endotracheal tube (ETT) early after intubation. Contaminated secretions in the ETT are associated with increased risk for microbial dissemination in the distal airways and increased resistance to airflow. We evaluated the effectiveness of micro computed tomography (MicroCT) for the quantification of ETT inner volume reduction in critically ill patients....