Modern X-ray structure analysis and advances in high-throughput robotics have allowed a significant increase in the number of conditions screened for a given sample volume. An efficient evaluation of the increased amount of crystallization trials in order to identify successful experiments is now urgently required. A novel approach is presented for the visualization of crystallization experimen...

background: the number of malaria cases is declining worldwide; however, it remains as a serious health problem. diagnosing unusual cases is the most im­portant issue to manage the problem. this study designed to describe the number of falciparum and vivax malaria infected patients referred to malaria reference labora­tory in tehran university of medical science from 2000 to 2012. methods: a re...

Abstract Anopheles stephensi mosquitoes share urban breeding sites with Aedes aegypti and Culex quinquefasciatus in the Republic of Djibouti. We present evidence that A. might be responsible for an increase malaria incidence this country. also document resistance Plasmodium falciparum to dihydroartemisinin/piperaquine.

Garciniavalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids,cleistopholine (2), O-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), wereisolated and characterized from Garcinia Parvifolia Miq. stem bark. Structural elucidation ofthese compounds was established by spectroscopic methods. Among them, alkaloids (2) and (4)exhibited antiplasmodial activi...

background: malaria is a big problem of public health in many tropical countries where socioeconomic development is deficient. four species of plasmodium are capable of infecting human: p. falciparum, p. malaria, p.vivax, p. ovale. southeastern corner of iran, including sistan and baluchestan, hormozgan and the tropical part of kerman province, are endemic region of malaria. this study aimed to...

garciniavalline (1), a novel aporphinoid alkaloid, in addition to four known alkaloids,cleistopholine (2), o-methylmoschatoline (3), (-)-oliveroline (4) and (-)-oliveridine (5), wereisolated and characterized from garcinia parvifolia miq. stem bark. structural elucidation ofthese compounds was established by spectroscopic methods. among them, alkaloids (2) and (4)exhibited antiplasmodial activi...

BACKGROUND Among the Plasmodium species that infect humans, adverse effects of P. falciparum and P. vivax have been extensively studied and reported with respect to poor outcomes particularly in first time mothers and in pregnant women living in areas with unstable malaria transmission. Although, other non-falciparum malaria infections during pregnancy have sometimes been reported, little is kn...

Severe malaria infection caused by Plasmodium falciparum is a global life-threatening disease and a leading cause of death worldwide. Intensive investigations have demonstrated that macrophages play crucial roles in control of inflammatory and immune responses and clearance of Plasmodium-falciparum-parasitized erythrocytes (PE). This paper focuses on how macrophage CD36 recognizes and internali...

We report a case of autochthonous falciparum malaria in a patient in Paris, France, in February 2013 who reported no recent travel to malaria-endemic countries. The parasite, Plasmodium falciparum, was possibly transmitted by an infective Anopheles mosquito carried in baggage from a malaria-endemic area.