Platelet-rich plasma (PRP) is obtained from a patient’s own peripheral blood, after centrifuging it, and has growth factors.[1] There are clinical studies indicating that PRP therapy may enhance muscle or tendon healing, and it accelerates the tissue regeneration after musculoskeletal injuries such as strain or contusion, during sports activities.[1,2] The application of these products is docum...

BACKGROUND Platelet-rich plasma (PRP) is an autologous concentration of human platelets in plasma. In this paper, we aimed to investigate the effect of PRP on hair growth. METHODS Platelet-rich plasma and platelet-poor plasma were prepared by sterile centrifugation and injected into shaved dorsal skin of mice (n = 10). Saline injection was used in the control group. The length of randomly plu...

Background: Platelet-rich plasma (PRP) has been advocated as one treatment for cartilage tissue regeneration. To date, several different platelet-rich formulations have been available, but a deep knowledge of their composition and mechanism of action in a specific clinical use is needed. The aim of this study was to investigate the effect of various PRP formulations on human chondrocytes in vitro.

Objective. The purposes of our present study were to evaluate the potential of platelet-rich plasma gel to enhance granulation tissue formation after open abdomen and to examine whether the effect was attributable to stimulating rapid neovascularization. Methods. Twenty-four rats underwent colon ascendens stent peritonitis surgery to induce sepsis, followed by intraperitoneal injection of nitro...

patients and methods seventy patients with chronic partial supraspinatus tears in magnetic resonance imaging were randomized into two groups; prp (n = 35) and pt (n = 35). before the treatment, at the end of the treatment and at the 12th month after the end of the treatment, range of motion (rom), visual analog scale (vas) for pain, disabilities of arm, shoulder and hand questionnaire (dash), n...

BACKGROUND Previous studies of bioactive molecules in platelet-rich plasma (PRP) have documented growth factor concentrations that promote tissue healing. However, the effects of leukocytes and inflammatory molecules in PRP have not been defined. HYPOTHESIS The hypothesis for this study was that the concentration of growth factors and catabolic cytokines would be dependent on the cellular com...

Abstract Background Non-healing surgical wounds is a risk in certain patients. Recently, allogenic plasma-rich-platelet (PRP) used such as regenerative treatment of different non-healing wounds. Purpose We explore the potential role using platelet-derived growth factors from single donor PRP, with freeze-thaw process, for scar ulcer. Methods have PRP preparation protocol that involved cycle cen...

Objective: To compare mean resting pain relief and passive external rotation improvement by Intra-articular Steroid versus intra-articular Platelet Rich Plasma injection in patients with adhesive capsulitis.
 Study Design: Prospective comparative study.
 Place Duration of Study: Armed Forces Institute Rehabilitation Medicine, Rawalpindi Pakistan, from Jan to Jun 2019.
 Methodolog...

BACKGROUND It is still not clear whether native or platelet count adjusted platelet rich plasma (PRP) should be used for platelet aggregation measurements. AIM To evaluate the necessity of using adjusted PRP in platelet function testing. METHODS Platelet aggregation with native PRP and adjusted PRP (platelet count: 250/nl, obtained by diluting native PRP with platelet poor plasma) was perfo...

Introduction. Platelet-Rich Plasma (PRP) is rich in growth factors, playing important role in tissue healing. The wide variation of reported protocols for preparation of PRP leads to variable compositions, which induce different biological responses and prevent results comparison. This study aims to highlight relevant aspects of the centrifugation step to obtain reproducible results and overall...