Scaffolding plays pivotal role in tissue engineering. In this work, a novel processing technique has been developed to create three-dimensional biodegradable polymer scaffolds with well-controlled interconnected spherical pores. Paraffin spheres were fabricated with a dispersion method, and were bonded together through a heat treatment to form a three-dimensional assembly in a mold. Biodegradab...

The dispersion state of barium titanate (BT) particle groups in self-assembled BT/poly-L-lactic-acid (PLLA) composites prepared under different fabrication conditions was investigated. In particular, the BT/PLLA/BT heterointerface BT aggregates by self-assembly process analyzed and effect BT/BT interface on dielectric properties BT/PLLA were fabricated adding particles granules with low high-sp...

UNLABELLED In order to improve implant success rate, it is important to enhance their responsiveness to the prevailing conditions following implantation. Uncontrolled movement of inflammatory cells and fibroblasts is one of these in vivo problems and the porosity properties of the implant have a strong effect on these. Here, we describe a hybrid system composed of a macroporous titanium structu...

Poly(L-lactide) (PLLA) is a semicrystalline thermoplastic which belongs to a biocompatible, biodegradable and bioresorbable polymers. PLLA also fulfills many requirements of the traditional nonbiodegradable packaging materials and it is therefore considered of great value from an ecological point of view due to its biobased character. Nonetheless, there are several aspects such as its slow crys...

The purpose of this study was to examine the growth and morphology of a salivary epithelial cell line (HSG) in vitro on several biodegradable substrata as an important step toward developing an artificial salivary gland. The substrates examined were poly-L-lactic acid (PLLA), polyglycolic acid (PGA), and two co-polymers, 85% and 50% PLGA, respectively. The substrates were formed into 20- to 25-...

Lipids and amphiphilic block copolymers spontaneously self-assemble in water to form a plethora of micelles and vesicles. They are typically fluidic in nature and often mechanically weak for applications such as drug delivery and gene therapeutics. Mechanical properties of polymeric materials could be improved by forming crystalline structures. However, most of the self-assembled micelles and v...

The influence of solid-liquid demixing, liquid-liquid demixing and vitrification on the morphology of polylactide membranes has been investigated. To study the effects of crystallization of polylactides on the membrane formation and morphology, polylactides of varying stereoregularity were used. The polymers applied were poly-L-lactide (PLLA) and copolymers with different molar ratios of L-lact...

The ability of apatite to form on the surface of biomaterials in simulated body fluid (SBF) has been widely used to predict the bone-bonding ability of bioceramic and bioceramic/polymer composites in vivo. Porous β-tricalcium phosphate/poly(L-lactic acid) (β-TCP/PLLA) composite scaffold was synthesized by new method. The ability of inducing calcium phosphate (Ca-P) formation was compared in sta...

Poly (L-lactic acid) (PLLA) is a biodegradable and biocompatible polymer that has been put forward as a promising material for therapeutic approaches aiming to restore neuronal function. The topographic cues present in PLLA-based scaffolds, defined by the technique used in their preparation, have been shown to play a role on the cellular behavior of adherent cells. Even though this interaction ...

Background: Polygluconate-B polymer (PGA) implants absorb quickly; and although they may not cause longterm joint or bone damage, they may cause synovitis and may not last long enough to effect healing. Poly-Llactic acid polymer (PLLA) implants absorb much more slowly but may cause delayed reactions or changes years after reconstruction. Objective: To compare the clinical and radiographic resul...