The present study assessed the value of bone marrow-mesenchymal stem cells (BM-MSCs) transformed by nucleus pulposus cells (NPs) for engineering of intervertebral discs. BM-MSCs and fetal NPs were cultured, planted onto polylactic acid-polyglycolic acid co-polymer (PLGA) and observed under inverted and scanning electron microscopes. PLGA scaffolds with adherent or suspended BM-MSCs and NPs were...

In recent year, biocompatible, biodegradable materials (linear polylactic acid-based urethanes) in the solid and/or liquid form have attracted tremendous attention in biomedical application particularly in stent coating. Low molecular weight poly (lactic acid) s (PLA), having narrow molecular weight distribution was by dehydropolycondensation method using tetraphenyltin as a catalyst. Hydroxyl ...

Two years after a quadrupled hamstring anterior cruciate ligament reconstruction using polylactic acid cross pin femoral fixation, a 32-year-old woman presented with symptoms of knee catching, locking, and stiffness. Diagnostic arthroscopy revealed a loose body in the anterior compartment of the knee which was determined to be part of the polylactic acid femoral fixation pin. The graft was inta...

Tissue engineering is an emerging field in biomedicine, holding enormous promise for regenerative medicine. Scaffolds, within which cells proliferate, are a controlling factor in tissue engineering applications. Upon fabrication, tissue scaffolds must undergo appropriate sterilization to eliminate contaminants. Current sterilization methods are either costly, time consuming, or ineffective. In ...

Localization of a ground glass nodule is a difficult challenge for thoracic surgeons, especially for ground glass opacities (GGOs) less than 10 mm in diameter. In this study we implement a new method for preoperative localization of pulmonary (GGOs). From October 2013 to December 2014, computed tomography-guided percutaneous polylactic acid injection localizations were performed for five pulmon...