نتایج جستجو برای: polymethylene green
تعداد نتایج: 140161 فیلتر نتایج به سال:
The synthesis of oligodeoxynucleotides d(AT)5 in which specific adenines are linked at C-8 position with dansyl fluorophores via a variable polymethylene spacer chain are reported. This was achieved by a strategy involving prelabelling at the monomeric stage followed by solid phase assembly of oligonucleotides to obtain regiospecifically labeled oligonucleotides. Several mono and polydansyl d(A...
Chimeras of tacrine and m-(N,N,N-Trimethylammonio)trifluoroacetophenone (1) were designed as novel, reversible inhibitors of acetylcholinesterase. On the basis of the X-ray structure of the apoenzyme, a molecular modeling study determined the favored attachment positions on the 4-aminoquinoline ring (position 3 and the 4-amino nitrogen) and the favored lengths of a polymethylene link between th...
Novel derivatives of the anti-HIV-1 agent, TSAO-T, bearing at the N-3 position a variety of polar, lipophilic, or aromatic groups linked to that position through flexible polymethylene linkers of different length, were prepared and evaluated for their anti-HIV activity. Several compounds (within the series of polar bearing groups) exhibited a 2-6-fold improved antiviral potency with regard to t...
Two types of distamycin-linked hydroxamic acids (DHA), which contain various lengths of polymethylene chains (PM-DHA) and relatively rigid phenylene ones (Ph-DHA), have been synthesized for the first time. Their DNA cleavage specificities were investigated by an end-labeled fragment cleavage experiment in the presence of vanadyl ion and hydrogen peroxide. The DNA cleavage by the PM-DHA x VO(II)...
Thioester-functionalized, siloxane-anchored, self-assembled monolayers provide a powerful tool for controlling the chemical and physical properties of surfaces. The thioester moiety is relatively stable to long-term storage and its structure can be systematically varied so as to provide a well-defined range of reactivity and wetting properties. The oxidation of thioesters with different-chain-l...
The positions o f continuous diffuse scattering streaks in electron diffraction patterns from oblique layer crystals isostructura 1 to monoclinic paraffins are predicted using the kinematical difference Fourier transform (DFT) model of Amoros and Amoros. However, indications of correlated chain m otions are found as was seen in a bimolecular rectangular layer structure. This correlated chain “ ...
نفوذپذیری و رواناب بهعنوان مهمترین فرآیندها و پدیدههای فیزیکی در یک حوضهآبخیز میباشند که ارزیابی برخی از خصوصیات و پارامترهای آنها از اهمیت خاصی برخوردار است. با توجه به اینکه در حوضههایآبخیز تخمین تمامی پارامترهای موردنیاز جهت بررسی میزان نفوذپذیری و رواناب میسر نمیباشد لذا انتخاب مدلی که بتواند پیشبینی با دقت قابلقبولی را ارائه کند، امری ضروری بهنظر میرسد. تحقیق حاضر با هدف مقای...
background & aim: in this study, is done during one-year research on blue–green and green algae for antimicrobial activity in mashhad suburb. aqueous, ether, and methanol extracts from 44 species blue – green algae and green algae were examined for antimicrobial properties against four bacteria (tow positive gram bacteria and tow negative gram bacteria) and tow fungous. material & meth...
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