Immunotherapy vaccines could extend survival in a handful of cancers. But personalizing treatment, payers argue, is not sustainable. Where should the line be drawn?

In this issue van Hout and Simoons describe a cost-effectiveness analysis of cardiovascular disease risk reduction by HMG coenzyme reductase inhibitors (statins). This exercise stems from the recommendations of the Netherlands Consensus Committee on Lipid Lowering. Costs of prescriptions and of major medical events (death, acute myocardial infarction, stroke, PTCA and CABG surgery) are consider...

With discount computer stores selling disk drives for a dollar per gigabyte (GB), how can enterprise storage systems be more than 100 times more expensive? What are the advantages of enterprise storage arrays? What role can low cost storage play in the information life cycle? Initiatives from companies such as Oracle are promoting lower cost storage alternatives in departmental and enterprise e...