Abstract Crisis provokes a sense of urgency often experienced as vertigo – the intense disorientation to where and when one belongs on temporal timeline pasts futures. The nauseating affects can be located in both crisis sudden rupture chronic condition former cliff-edge moment schism historical continuity induces dizziness falling, latter defined by inescapability suffocating captivity. This a...

Allosensitized children listed with a requirement for a negative prospective crossmatch have high mortality. Previously, we found that listing with the intent to accept the first suitable organ offer, regardless of the possibility of a positive crossmatch (TAKE strategy), results in a survival advantage from the time of listing compared to awaiting transplantation across a negative crossmatch (...

Impulsivity is a multifaceted trait with substantial implications for human well-being. One facet of impulsivity is negative urgency, the tendency to act impulsively in response to negative affect. Correlational evidence suggests that negative affect magnifies impulsive behavior among individuals with greater negative urgency, yet causal evidence for this core pillar of urgency theory is lackin...

BACKGROUND The choice of endpoints is crucial for proper evaluation of agents in clinical trials of irritable bowel syndrome (IBS). In a recently published draft guidance for IBS from the United States Food and Drug Administration (FDA), urgency was not considered an appropriate primary endpoint. The FDA's position is that it is not clear how patients with diarrhea-predominant IBS (D-IBS) "defi...

PURPOSE To investigate the change in urinary urgency and predictors of urgency improvement after holmium laser enucleation of the prostate (HoLEP) in men with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS We retrospectively analyzed the medical records of patients who were treated with HoLEP for BPH and had preoperative urgency measuring ≥3 on a 5-point urinary sensation scale. Th...

OBJECTIVE The aim of this study was to explore the relationship between voided volume (VV) and urge to void among patients with lower urinary tract symptoms. MATERIAL AND METHODS Consecutive adult patients (aged 23-90 years) were enrolled, and completed a 24 h bladder diary and the Urgency Perception Scale (UPS). Patients were categorized as urgency or non-urgency based on the Overactive Blad...

Among 108 consecutive patients with myelomeningocele aged 5-12 years initially treated by a selective policy, seven (6.5%) achieved spontaneous urinary continence, five with normal micturition and two with urgency. All had positive conus reflexes and incomplete cord lesions which, with one exception, comprised motor as well as sensory sacral sparing.