background: in this work investigation of the normoxic pagat polymer gel dosimeter such as sensitivity, the r2-dose response with post time and the percentage depth dose (pdd) of pagat polymer gel dosimeter have been undertaken. materials and methods: using mri, the formulation to give the maximum change in the transverse relaxation rate r2 was determined to be 4.5% n,n'-methylenbis- acryl...

The purpose of this study was to evaluate the effect of silanization and light-irradiation on bonding between a fiber post and different resin-based luting agents. Sixty silicium fiber posts (Easy Post) were divided into 10 groups according to the type of resin-based luting agent employed, whether the post surface was silanized, whether the adhesive was light-irradiated, and whether Calibra lut...

Adenoid cystic carcinoma (ACC) of the tracheo-bronchial tree is an uncommon tumor. ACC is generally diagnosed as a lesion involving the trachea; endobronchial involvement is extremely rare. At present, surgical resection and reconstruction followed or not by post-operative irradiation is considered as the therapy of choice for definitive cure. Endoscopic treatment of these tumors is uncommonly ...

The treatment of supratentorial malignant gliomas has continued to be a major problem for neurosurgeons and oncologists. Post-operative conventional radiotherapy is known to prolong survival and to enhance the quality of life. Local persistence of tumor kills the majority of patients. Fast neutron irradiation is being utilized to treat malignant gliomas based on its reputed radiobiological adva...

The aim of the study was to compare in vivo cardiac function with ex vivo cardiac performance after local heart irradiation in the same rat. Left ventricular ejection fraction (LVEF) was measured in vivo by radionuclide ventriculography in Sprague-Dawley rats up to 16 months after a single dose of 20 Gy. Four days after in vivo measurements, cardiac performance was determined ex vivo, using the...

Brainstem auditory evoked potentials (BAEP) were recorded in two patients with nasopharyngeal carcinoma (NPC) irradiated 14 and three years ago respectively and compared with 15 healthy controls. The patients had features of post-irradiation myelopathy of the brainstem with reduced gag reflex, unilateral vocal cord paralysis and fasciculation of the tongue. The first patient had a blind left ey...

We have studied the effects of 2-deoxy-D-Glucose (2-DG) on the recovery of potentially lethal damage (PLDR), repair of chromosomal DNA, cyclobutane pyrimidine dimers (CPDs), reverse mutation and gene-conversion in UVC (254 nm) irradiated yeast. As studied by pulsed-field gel electrophoresis, post-irradiation chromosomal DNA repair kinetics in a phosphate buffer (PB) with 10 mM glucose (G) was b...

Cytoplasmic alterations in human epidermis irradiated with ultraviolet light have been described by light microscopy (1, 2). Pronounced changes occurred in cells of the basal and spinous layers at the peak of the erythema reaction (twenty-four to thirty hours after irradiation). At this time, cells in the spinous layer developed homogeneous, deeply staining cytoplasm and pyknosis of nuclei. Tbe...

BACKGROUND Lymphocyte infiltration is a common feature of radiation-induced pneumonitis and fibrosis, but their contribution to the pathogenic processes is still unclear. Here, we addressed the impact of thorax irradiation on the T cell compartment with a focus on immunosuppressive regulatory T cells (Treg). METHODS C57BL/6 wild type mice (WT) received anesthesia only (sham controls, 0 Gy) or...