BACKGROUND A consensus is lacking on a uniform reconstructive algorithm for patients with locally advanced breast cancer who require postmastectomy radiotherapy. Both delayed autologous and immediate prosthetic techniques have inherent advantages and complications. The study hypothesis is that implants are more cost effective than autologous reconstruction in the setting of postmastectomy radio...

http://dx.doi.org/10.1093/infdis/173.3.592 7. Drexler JF, Corman VM, Lukashev AN, Brand JMA, van den Gmyl AP, Brünink S, et al. Evolutionary origins of hepatitis A virus in small mammals. Proc Natl Acad Sci U S A. 2015;112:15190–5. http://dx.doi.org/10.1073/pnas.1516992112 8. Drewe JA, O’Riain MJ, Beamish E, Currie H, Parsons S. Survey of infections transmissible between baboons and humans, Cap...

LEARNING OBJECTIVES After reading this article, participants should be able to: 1. Understand the evidence regarding the timing of expander/implant breast reconstruction in the setting of radiation therapy. 2. Discuss the implications of a patient's risk factors for possible outcomes and complications of expander/implant breast reconstruction. 3. Implement proper prophylactic antibiotic protoco...

BACKGROUND The techniques of breast reconstruction have evolved and matured over the past 25 years. Recent studies have proven the benefit of breast reconstruction for breast cancer patients. METHODS The authors reviewed the recent literature on the techniques of breast reconstruction and the effects of reconstruction on patients following surgery for breast cancer. The findings in recent stu...

Background Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefi t in women with only one to three positive lymph nodes is uncertain. We aimed to assess the eff ect of radiotherapy in these women after mastectomy and axillary dissection.

Classic or idiopathic Sweet syndrome is a neutrophilic skin disorder characterized by the association of cutaneous manifestations and systemic symptoms. The skin lesions tend to occur on the face, neck, chest, and arms, and present as painful papules, nodules, or erythematous plaques. Systemic symptoms, such as general malaise, joint pain, and neutrophilic leukocytosis, may appear days earlier ...

BACKGROUND The therapeutic role of postmastectomy radiation therapy has been demonstrated both in locally advanced breast cancer and in other high-risk conditions. Implant-based breast reconstruction for irradiated patients can generate higher complication rates. In this study, the authors observed the effects of radiation on temporary expanders and permanent implants. The estimate of the total...

PURPOSE To evaluate the technique, dosimetry, acute and late toxicity, local control (LC), and overall survival (OS) with the use of computed tomography (CT)-based postmastectomy electron beam therapy (PMEBT) in high-risk patients. METHODS AND MATERIALS From 1990 to 2000, 118 patients with pathologic stage I-IIIB breast cancer underwent PMEBT of the chest wall (CW) (n = 3), CW and supraclavic...