BACKGROUND Oral opioid formulations contribute to postoperative analgesia. In this study, we evaluated the perioperative application of oral controlled-release oxycodone to reduce postoperative IV morphine consumption and opioid side effects after lumbar discectomy. METHODS Forty patients scheduled for elective lumbar discectomy over 1 or 2 levels were included in this prospective, randomized...

BACKGROUND Improvement in patient outcome and reduced use of medical resources may result from using epidural anesthesia and analgesia as compared with general anesthesia and intravenous opioids, although the relative importance of intraoperative versus postoperative technique has not been studied. This prospective, double-masked, randomized clinical trial was designed to compare alternate comb...

conclusions the most comfortable postoperative women were those in luteal phase without history of pms group. results patients with pms presented higher pain sensation and analgesia request (p = 0.003). patients in luteal phase showed less pain and analgesia request in two out of five studied outcomes (p = 0.075). patients and methods a total of 140 women in in postoperative period were assigne...

Although most randomized clinical trials conclude that the addition of continuous peripheral nerve blockade (CPNB) decreases postoperative pain and opioidrelated side effects when compared with opioids, studies have included relatively small numbers of patients and the majority failed to show statistical significance during all time periods for reduced pain or side effects. We identified studie...

ANESTHESIOLOGY is a dynamic specialty that has adapted well to demands from patients to improve the quality of their care and pressures from the healthcare industry to achieve this in a cost-effective fashion. The aging of the population undergoing surgical procedures, increasing proportion of surgical procedures performed in an outpatient setting, and emphasis on cost containment have led clin...

Zellweger H, Antonik A. Newborn screening for Duchenne muscular dystrophy. Pediatrics 1975 ;55 :30-4. 2 Firth M, Gardner-Medwin D, Hosking G, Wilkinson E. Interviews with parents of boys suffering from Duchenne muscular dystrophy. Dev Med Child Neurol (in press). 3 Beckmann R, Scheuerbrandt G. Muskeldystrophie (Duchenne)Friiherkennung, CK-Screeningtest, Konsequenzen. Der Kinderarzt 1977;8 :313-...

In recent years, there has been an increasing interest in local infiltration analgesia (LIA) as a technique to control postoperative pain. We conducted a systematic review of randomized clinical trials investigating LIA for total knee arthroplasty (TKA) and total hip arthroplasty (THA) to evaluate the analgesic efficacy of LIA for early postoperative pain treatment. In addition, the analgesic e...

Editor’s key points † Thoracic epidural analgesia is associated with rare but potentially serious complications. † In the setting of lung surgery single-shot intercostal block (ICB) offers an alternative modality of postoperative regional analgesia. † This study compared PCEA with single-shot ICB combined with PCA. ICB with PCA was not as effective as PCEA with respect to postoperative pain con...