Protein phosphatase 1 (PP-1) is known to be a critical component of eukaryotic cell cycle progression. In vitro, our previous studies showed that cdc2 kinase phosphorylates Thr-320 (T320) in PP-1, and that this leads to inhibition of enzyme activity. To examine directly the phosphorylation of PP-1 in intact mammalian cells, an antibody has been prepared that specifically recognizes PP-1C alpha ...

Irradiation of polymers is one of the most effective and economical methods for modifying their properties and for changing their applications. In this study, an extrusion grade polypropylene (PP) was treated by electron beam irradiation to produce a PP suitable for injection molding. Irradiation was carried out at different doses (0-80 kGy) under atmosphere air and at ambient temperature. Melt...

The term ‘fragmentation functions’ is widely used for two related if conceptually different sets of functions describing final-state single particle energy distributions in hard scattering processes (see Refs. [1,2] for introductory reviews, and Refs. [3,4] for summaries of recent experimental and theoretical research in this field). The first are cross-section observables such as the functions...

We present a three-body formalism describing the final-state interaction effects in the pp → ppη reaction close to threshold. We derive a three-body enhancement factor devised in such a way that all three pair-wise interactions are regarded on equal footing. The enhancement factor is obtained by expanding the three-particle wave function in hyperspherical harmonics. It has been shown that close...

Background and objectives:  High concentration of preservatives in food may result in gastrointestinal disturbances whereby some patients suffering from asthma, rhinitis, or urticaria. The aim of this study is the introduction and optimization a new method for simultaneous determination of four preservatives (SB, PS, MP, PP) in foodstuff by high performance liquid chromatography. Materi...

In this study, we characterized the effects of the protein phosphatases type 1 (PP 1) and type 2A (PP 2A) inhibitor cantharidin in endothelial cells. We identified catalytic subunits of PP 1alpha, PP 2Aalpha, and PP 2Abeta immunologically in bovine aortic endothelial cells. Moreover, we detected mRNAs coding for catalytic subunits of PP 1alpha, PP 1beta, and PP 2Aalpha by hybridization with spe...

Glycogen synthase is activated by protein phosphatase type-1 (PP-1). The spontaneous PP-1 activity accounts for only a small fraction of total PP-1 activity, which can be exposed by trypsin digestion of inhibitor proteins in the presence of Mn2+. We determined total PP-1 activity in muscle biopsies from insulin-sensitive and -resistant nondiabetic Pima Indians. Inhibitor-2 sensitive PP-1 repres...

Over the last few years, a number of investigations have been conducted to explore the low cost sorbents for the decontamination of toxic materials. Undoubtedly, agricultural waste mass is presently one of the most challenging topics, which has been gaining attention during the past several decades. Wastes are very cheap and easily available material in production of sorbent. Therefore, the Rea...