OBJECTIVE We attempted to reveal the changes of the human telomerase reverse transcriptase (hTERT) alternative splicing pattern in gastric carcinogenesis. METHODS Three alternative splicing sites (alpha, beta, gamma) were selected and designed PCR primer. The expression of 8 hTERT alternative splicing variants (ASVs) in normal gastric mucosa, precancerous lesions and gastric cancer were detec...

Background: The clinical and pathological evaluation of oral lesions are very important in this field. The purpose of this study was to assess clinico- pathological agreement on 232 cases with oral lesion s.Methods: The consecutive files of 232 patients with oral lesions from pathological laboratory archives of Babol Dental faculty and Shahid Beheshti Hospital were reviewed and the data include...

: One of the most prevalent cancers, cervical cancer is also leading cause mortality for women in underdeveloped nations. A fundamental test finding infections and precancerous diseases Papanicolaou smear. This study aims to comprehend function screening detecting premalignant, malignant, non-neoplastic lesions as well prevalence different who received a traditional pap smear technique. We scre...

Introduction. Identification of persons with a high oncological risk to squamous cell carcinoma the head and neck region is an urgent problem for early diagnosis this disease. The activity circulating proteasomes can be criterion predicting larynx oral cavity cancers in patients precancerous diseases upper respiratory gastrointestinal tracts. aim study investigate chymotrypsin-like caspase-like...

BACKGROUND Cervical cancer is the second most prevalent cancer among women in the developing countries including Ethiopia. Precancerous lesions can be developed and risk to the development of cervical cancer over time. Early identification of the precancerous lesion and its risk factor is paramount in preventing cervical cancer. However, the determinants of cervical precancerous lesions are not...

background: the clinical and pathological evaluation of oral lesions are very important in this field. the purpose of this study was to assess clinico- pathological agreement on 232 cases with oral lesion s.methods: the consecutive files of 232 patients with oral lesions from pathological laboratory archives of babol dental faculty and shahid beheshti hospital were reviewed and the data include...

Objective. To assess the prevalence and identified associated risk factors for precancerous cervical cancer lesions among HIV-infected women in resource-limited settings in Kenya. Methods. HIV-infected women attending the ART clinic at the Nazareth Hospital ART clinic between June 2009 and September 2010. Multivariate logistic regression model with odds ratios and 95% confidence intervals (CI) ...

The histological criteria of uterine cervix lesions are well known. However, there is a poor diagnostic reproducibility especially concerning lowgrade precancerous lesions. Therefore, the aim of our study was to evaluate the utility of p16 overexpression as a surrogate biomarker of precancerous lesions of the uterine cervix. A retrospective study was carried out by the International Center for ...