Disease etiology may be regarded as a consequence of both genotypic and biochemical phenomena, which impact individual patients in different ways. Disease prognosis, beneficial treatment response, and susceptibility to adverse drug effects are often intimately tied to individual biology. Clinical and genetic biomarkers applied individually or in concert are increasingly used to stratify patient...

Abstract Multiple sclerosis (MS) is a serious neurological disease, the actual worldwide prevalence of which estimated to be 2,8 million people (35,9 per 100,000). During course MS, various symptoms and its complications result in raising patient disability, range from skeletal muscles impairment, losses cognitive functions. Achieving control over MS progression appears crucial treatment. This ...