نتایج جستجو برای: prednisone

تعداد نتایج: 9193  

Journal: :Blood 1990
R Storb M Pepe C Anasetti F R Appelbaum P Beatty K Doney P Martin P Stewart K M Sullivan R Witherspoon

One hundred forty-seven consecutive patients with leukemia, myelodysplastic syndrome, or aplastic anemia were treated by marrow grafts from genotypically HLA-identical siblings (n = 122) or HLA-haploidentical family members (n = 25). Haploidentical recipients differed from their donors for no more than one HLA locus on the nonshared haplotype. All were given postgrafting immunosuppression with ...

2010
Frank Buttgereit Rieke Alten Gisela Döring Maurizio Cutolo Erika Gromnica-Ihle Stephan Witte RIEKE ALTEN GISELA DÖRING MAURIZIO CUTOLO ERIKA GROMNICA-IHLE STEPHAN WITTE FRANK BUTTGEREIT

Objective. To investigate the effects of longterm low-dose chronotherapy with modified-release (MR) prednisone for rheumatoid arthritis (RA) on the hypothalamus-pituitary-adrenal (HPA) axis as part of the Circadian Administration of Prednisone in Rheumatoid Arthritis (CAPRA-1) study. This consisted of a 3-month active-controlled phase and a 9-month open-label extension with MR prednisone includ...

2013
William Dunlop Itrat Iqbal Ifty Khan Mario Ouwens Louise Heron

BACKGROUND Assessing the cost-effectiveness of treatments in rheumatoid arthritis (RA) is of growing importance due to the chronic nature of the disease, rising treatment costs, and budget-constrained health care systems. This analysis assesses the cost-effectiveness of modified-release (MR) prednisone compared with immediate-release (IR) prednisone for the treatment of morning stiffness due to...

2014
Xingxing Zhang Xiaochuan Wu Lan Xiong Zhuwen Yi Qingnan He Xiaojie He Shuanghong Mo

Introduction. Dysregulation of CD4+ T cell subsets participates in the pathogenesis of immunoglobulin A nephropathy (IgAN). Vitamin D has immunomodulatory functions. This study aims to investigate the regulatory effect of vitamin D3 on T helperregulatory T (Th17-Treg) cells balance in rats with IgAN. Materials and Methods. Sprague-Dawley rats were randomly assigned to a normal group (n = 6), an...

Journal: :American journal of kidney diseases : the official journal of the National Kidney Foundation 1997
V K Bansal J A Beto

The best therapeutic choice in lupus nephritis remains shrouded in a body of controversial literature. The purpose of this review was to assess and compare by meta-analysis the efficacy of therapeutic agents used in the treatment of lupus nephritis using outcomes of end-stage renal disease (ESRD) and total mortality. An exhaustive search was performed using MEDLINE (1970 to 1995) and manual sea...

Journal: :Clinical and experimental rheumatology 2013
Maurizio Cutolo Luca Iaccarino Andrea Doria Marcello Govoni Alberto Sulli Claudio Marcassa

OBJECTIVES In rheumatoid arthritis (RA), low-dose glucocorticoids (GCs) demonstrate disease-modifying potential when added to DMARDs. Modified-release (MR) prednisone taken at bedtime (released 2am) is more effective than immediate-release (IR) GC taken in the morning. METHODS In an open-label observational study, 950 RA outpatients (mean age 57 ± 13 years; 75% females) treated with GCs and D...

Journal: :The British journal of ophthalmology 2005
M J Kupersmith G Ying

AIM The optimal treatment of ocular myasthenia gravis (OMG) remains unknown. The authors evaluated the efficacy of prednisone and pyridostigmine in reducing diplopia, ocular motor dysfunction, and ptosis in patients with OMG. METHODS Review of records from a clinical database from one neuro-ophthalmology service of patients presenting with OMG between 1990 and 2002, excluding those who develo...

Journal: :Chest 1998
M Selman G Carrillo J Salas R P Padilla R Pérez-Chavira R Sansores R Chapela

STUDY OBJECTIVE We compared the long-term efficacy of the combination of colchicine and/or D-penicillamine with prednisone, in comparison to prednisone alone in patients with idiopathic pulmonary fibrosis (IPF). DESIGN Nonrandomized prospective study in patients with IPF confirmed by biopsy specimen. SETTING National Institute of Respiratory Diseases, Mexico. PATIENTS Fifty-six IPF patien...

Journal: :Blood 2016
Anja Möricke Martin Zimmermann Maria Grazia Valsecchi Martin Stanulla Andrea Biondi Georg Mann Franco Locatelli Giovanni Cazzaniga Felix Niggli Maurizio Aricò Claus R Bartram Andishe Attarbaschi Daniela Silvestri Rita Beier Giuseppe Basso Richard Ratei Andreas E Kulozik Luca Lo Nigro Bernhard Kremens Jeanette Greiner Rosanna Parasole Jochen Harbott Roberta Caruso Arend von Stackelberg Elena Barisone Claudia Rössig Valentino Conter Martin Schrappe

Induction therapy for childhood acute lymphoblastic leukemia (ALL) traditionally includes prednisone; yet, dexamethasone may have higher antileukemic potency, leading to fewer relapses and improved survival. After a 7-day prednisone prephase, 3720 patients enrolled on trial Associazione Italiana di Ematologia e Oncologia Pediatrica and Berlin-Frankfurt-Münster (AIEOP-BFM) ALL 2000 were randomly...

Journal: :Neurobiology of learning and memory 2006
E Sherwood Brown Laura Beard Alan B Frol A John Rush

Corticosteroids are essential for life and an integral part of the stress response. However, in excess, corticosteroids can be associated with a variety of effects on the brain including hippocampal atrophy and even neuronal death, mood changes, and declarative memory impairment. The magnitude of mood change in patients receiving prednisone is reportedly associated with previous lifetime cortic...

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