OBJECTIVE To evaluate a new strategy for comprehensive chromosome screening at the blastocyst stage. DESIGN Clinical research study. SETTING An IVF clinic and a specialist preimplantation genetic diagnosis laboratory. PATIENT(S) Forty-five infertile couples participated in the study. The mean maternal age was 37.7 years, and most couples had at least one previous unsuccessful IVF treatmen...

As numerical and structural defects in chromosomes are an inevitable consequence of IVF, Pre-implantation genetic diagnosis and screening (PGD/PGS) methods are used for detecting abnormalities in embryos before implantation to the uterus to increase the successful rate of IVF. Pre-implantation genetic diagnosis and screening approaches can be achieved by different techniques such as NGS, CGH an...