OBJECTIVE To evaluate the safety and efficacy of Isosorbide mononitrate (IMN) as a cervical ripening agent prior to induction of labour in term pregnant women. MATERIALS AND METHODS A randomized placebo-controlled study was conducted on 100 term singleton pregnancies planned for induction of labour. The participants were randomly assigned to two groups. One group received 40 mg IMN and the ot...

The ability to switch metabolic flow from one pathway to another at a desired point in a bioprocess expands the horizons of metabolic engineering. Such an externally inducible switch can be realized by embedding synthetic operons behind tow corss-regulated promoters. This results in coordinated cessation of transcription of one operon while transcription of a second operon is simultaneously act...

The participation of renal metallothionein (MT) in the toxicity and antitumor activity of cis-diamminedichloroplatinum(II) (cis-DDP) in male mice was examined. Preinduction of MT in the kidney by the s.c. administration of bismuth compounds decreased the lethality and renal and gastrointestinal toxicity caused by a single s.c. injection of cis-DDP. In the present study a correlation between the...

In order to study the effects of CO2 laser moxibustion on the pain and inflammatory cytokine expression in the spinal dorsal horn of rats with monosodium iodoacetate- (MIA-) induced knee osteoarthritis (KOA), we designed an experiment by randomly assigning 8 SD rats into 3 groups, namely, a CO2 laser moxibustion group, a sham treatment group, and a blank control group. The treatment group recei...

Epidemiological studies have shown an association between consump tion of alcoholic beverages and increased occurrence of large bowel carcinoma, but studies in experimental models of colonie carcinogenesis have produced conflicting results. We assessed the effects of chronic dietary ethanol consumption during the preinduction and induction phase (period of acclimatization and carcinogen adminis...

Epidemiological studies have shown an association between consumption of alcoholic beverages and increased occurrence of large bowel carcinoma, but studies in experimental models of colonic carcinogenesis have produced conflicting results. We assessed the effects of chronic dietary ethanol consumption during the preinduction and induction phase (period of acclimatization and carcinogen administ...

The efficacy of intracervical Foley catheter with misoprostol (PGE1) and dinoprostone (PGE2) for preinduction cervical ripening, induction of labour, mode of delivery, induction to delivery interval and maternal complications has been compared.. Women who were admitted to hospital and met criteria for entrance in the trial were counseled and enrolled after informed consent. Inclusion criteria i...

Background: Preinduction cervical ripening has a great influence on induction of labor. For labor various methods are used. Mechanical Foleys catheter with or without extra-amniotic saline. Various pharmacological misoprostol, dinoprostone, and oxytocin.Methods: This was prospective observational study conducted 100 patients 50 in each group the department obstetrics gynecology, Government Medi...