INTRODUCTION To evaluate the accuracy of transcutaneous bilirubin measurement in a large population of newborn infants, before and during the phototherapy. PATIENTS AND METHODS A single Bilicheck instrument was used for transcutaneous measurements. A photo-opaque patch was positioned over the measurement site prior to starting phototherapy. Transcutaneous bilirubinometry was conducted on an u...

Pulmonary hypertension (PH) of the newborn is a severe complication that occurs more frequently in term infants but can be demonstrated also in preterm infants. The incidence of PH in preterm infants is currently unknown because it is often masked by the contemporary respiratory distress syndrome (RDS), there are not important echocardiography studies in the early transitional period assessingt...

Over the past 40 years, the norms on who is to make treatment decisions for newborns, and on what standards, have been significantly altered and revised. Today the standard for treatment of newborns is the "best interest" of the child. A recent ruling of the Texas Supreme Court authorizing a doctor to resuscitate a potentially viable very premature newborn over the parents' objection is a chall...

The pharmacokinetic properties of mezlocillin were evaluated in newborn infants. Mean peak and trough concentrations of drug in plasma, after 75 mg of mezlocillin per kg given intravenously, were 252 and 72 micrograms/ml, respectively, in infants who were less than 38 weeks gestation and less than or equal to 7 days old, compared with 139 and 9 micrograms/ml, respectively, in infants greater th...

After birth, continuous transplacental transfer of glucose is interrupted. Neonates have to provide brain and vital organs with sufficient glucose. In term newborn infants, this is accomplished through well-coordinated hormonal and metabolic adaptive changes. During the first week of life, preterm infants are at high risk of abnormal glucose homeostasis. They are at risk of hypoglycemia due to ...

Introduction Preterm birth is the leading cause of child mortality. This study aimed to develop and validate programmatically feasible accurate approaches estimate newborn gestational age (GA) in low resource settings. Methods The WHO Alliance for Maternal Newborn Health Improvement (AMANHI) recruited pregnant women from population-based cohorts five countries (Bangladesh, Ghana, Pakistan, Tanz...

OBJECTIVE The objective was to study the possible association among maternal migraine during pregnancy, pregnancy complications, and the delivery outcomes: sex ratio, gestational age/birth weight and preterm birth/low birth weight. STUDY DESIGN The population-based large data set of newborn infants without any defects of the Hungarian Case-Control Surveillance System of Congenital Abnormaliti...

Birth weight, length and circumferences of the head, chest and arm are key measures of newborn size and health in developing countries. We assessed maternal socio-demographic factors associated with multiple measures of newborn size in a large rural population in Bangladesh using partial least squares (PLS) regression method. PLS regression, combining features from principal component analysis ...

Osteopenia of prematurity and neonatal metabolic bone disease are terms used to describe the reduced skeletal mineralization seen in preterm babies at term as compared with those who have remained in utero. During the last trimester of pregnancy there is a rapid accretion of calcium and phosphorus due to active transport across the placenta(l). The osteopenia makes the preterm newborn more susc...

Predictive relations between maternal variables and outcome status for 199 pairs of newborn twins were evaluated. The maternal independent variables included pregravid weight, weight at end of pregnancy, weight gain, age, parity, height, socioeconomic status, years of education, and body mass index. The twin dependent variables included birthweight, birth length, 5-min Apgar score, number of da...