Preterm birth still causes significant mortality and morbidity in newborns, despite modern advancements preterm care. The gut microbiota is the most microbial colonization human body plays a role supporting healthy body. infants are susceptible to dysbiosis, which thought contribute many adverse outcomes of prematurity, such as necrotizing enterocolitis (NEC), late-onset sepsis (LOS), developme...

Congenital cytomegalovirus (CMV) infection is the leading cause of mental retardation and hearing impairment. Examination for the presence of CMV infection was carried out in a selected population of 70 neonates. Urine samples were tested for CMV by means of a nested polymerase chain reaction. CMV was detected in 6 (16.7%) of the 36 preterm newborns and in 5 (14.7%) of the 34 full-term newborns...

BACKGROUND & AIMS Nutritional supplementation with polyunsaturated fatty acids is important in preterm infants neurodevelopment, but it is not known if the omega-6/omega-3 ratio affects this process. This study was designed to determine the effects of a balanced contribution of arachidonic acid in very preterm newborns fed with formula milk. METHODS This was a randomized trial, in which newbo...

INTRODUCTION The term “low birth weight” (< 2500 g) encompasses preterm newborns and term newborns small for gestational age (SGA) (< P10). The World Health Organization de nes underweight as a birth weight < P3 of weight/ age. There is no consensus at an international level about which standards and/or references related to birth weight for gestational age (GA) should be used to assess SGA and...

background: nasal continuous positive airway pressure (ncpap) is an effective method of ventilation in newborns with respiratory distress syndrome (rds). using an appropriate nasal skin care protocol is identical to prevention or reduction of nasal skin breakdown in those who receive ncpap. this study aimed to investigate the effectiveness of an evidence-based clinical care protocol on nasal sk...

Background: the sucking development pattern of the preterm newborn (PTNB) in the neonatal period is important for an effective sucking and oral motor development. The establishment of a safe and efficient feeding in pre-term newborns is related to a rhythmic and coordinated sucking. Nonnutritive sucking stimulation can have an influence on the development of sucking and the development of sucki...

BACKGROUND Histological chorioamnionitis (HC) is an intrauterine inflammatory process highly associated with preterm birth and adverse neonatal outcome. HC is often clinically silent and diagnosed postnatally by placental histology. Earlier identification could facilitate treatment individualisation to improve outcome in preterm newborns. AIM Develop a clinical prediction rule at birth for HC...

BACKGROUND The sucking development pattern of the preterm newborn (PTNB) in the neonatal period is important for an effective sucking and oral motor development. The establishment of a safe and efficient feeding in pre-term newborns is related to a rhythmic and coordinated sucking. Nonnutritive sucking stimulation can have an influence on the development of sucking and the development of suckin...

Background: Tremendous difficulties are imposed on families with preterm and premature babies, both at birth and during their lifetime. The present study aimed at evaluating the potential economic impact of preterm and premature birth in Iran. &nbsp;&nbsp; Methods: In this descriptive cross-sectional study (2014-2015), we studied preterm and premature newborns, who have been subjected to hospi...

The clinical management of a patent ductus arteriosus (PDA) in preterm newborns is a controversial topic, and despite nearly three decades of research, varying opinions remain. This dilemma stems from uncertain causal linkage between PDA and neonatal comorbidities, as well as the lack of clear evidence showing that benefits of treatment outweigh risks. There has been a general shift in the mana...