introduction: primary ovarian failure (pof) is a syndrome composed of amenorrhea, estrogen deficiency and follicular stimulating hormone (fsh) of menopausal ranges in young women. in this article, we report a case of primary amenorrhea that presented with full term pregnancy.case presentation: a 29-year old woman with a history of primary amenorrhea attended hospital with full term pregnancy. s...

primary complement deficiencies are rare and two related patients are reported here. the first patient is a 41- year- old man with eighteen episodes of pneumo¬coccal meningitis and other purulent infections. the serum c3 level was checked at three separate times, showing that this was a primary c3 deficient case; other immunological tests were however normal. this patient now takes prophylactic...

PURPOSE Use of the T cell-dependent neoantigen bacteriophage ΦX 174 has been described since the 1960s as a method to assess specific antibody response in patients with primary immunodeficiencies. We reviewed a cohort of patients at Duke University Medical Center who received immunization with bacteriophage and report the clinical utility and safety of the immunization, as well as patient chara...

The primary purpose of this systematic review was to produce an evidence-based review of the literature as a means of informing current clinical practice in the recognition, diagnosis and management of patients with suspected primary antibody deficiency. Randomized controlled trials (RCTs) were identified from a search of MEDLINE, EMBASE, The Cochrane Library, DARE (CRD website) and CINAHL by c...

Aim To evaluate health-related quality of life, mental health and treatment-related stress responses in children with primary antibody deficiency both their parents. Methods Children parents completed the standardised questionnaires Pediatric Quality life Inventory, Strength Difficulties Questionnaire Impact Event Scale. Parents also regarding own life. The results were compared to those health...